Challenges in the care of patients with systemic lupus erythematosus and lupus nephritis in Latin America

Introduction: Systemic lupus erythematosus is a rare disease; however, it is one of the leading causes of death in young women, in particular those with a larger percentage of Amerindian ancestry. Areas covered: This article provides a review of the epidemiology of systemic lupus erythematosus and lupus nephritis in the Latin American population, as well as the challenges for the appropriate management of these patients, including delays in diagnosis, healthcare access, and access to new drugs in the region. We propose potential solutions to these problems, including activities to be done by governments, healthcare systems, and healthcare professionals. Expert opinion: Systemic lupus erythematosus, in particular lupus nephritis, is more severe in patients with a larger percentage of Amerindian ancestry; this is influenced not only by their ancestry but also by their sociodemographic characteristics, including access to healthcare and the availability of new drugs. Several strategies to improve diagnosis, management, and access to medication need to be done to reduce these disparities.