Understanding Risk Factors for Poor Outcomes in a Multiethnic Longitudinal Cohort: The LUMINA (Lupus in Minorities: Nature vs. Nurture) Experience (LUMINA LXXXII)
- Luis Alonso González,
- Guillermo J. Pons-Estel,
- Sergio M.A. Toloza,
- ,
- Graciela S. Alarcón(corresponding author)
- Universidad de Antioquia,
- Grupo Oroño-Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR),
- Hospital Provincial de Rosario,
- Hospital San Juan Bautista,
- ,
- Universidad Científica del Sur
Research Output:
Contribution to journal
Review article
Peer-reviewPublication Information
Output type
Research Output:
Contribution to journal
Review article
Peer-reviewOriginal language
EnglishPages from-to (Number of pages)
Pages 55-64 (10 pages)Journal (Volume, Issue Number)
Rheumatic Disease Clinics of North America (Volume 47, Issue 1)Publication milestones
- Published - 02/2021
Publication status
Published - 02/2021
ISSN
0889-857XPublication IDs
- Scopus: 85094809267
- PubMed: 34042054
Abstract
The Lupus in Minorities: Nature Vs Nurture (LUMINA) cohort has placed Hispanics on the lupus map in the United States. Texan Hispanic and African American patients experience, overall, worse outcomes than the Caucasian and Puerto Rican Hispanic patients. The genetic component of ethnicity is important early in the disease course whereas socioeconomic factors become more important subsequently. The role of hydroxychloroquine in preventing damage accrual and reducing mortality in lupus patients is a major contribution of LUMINA.
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