Prompt Initiation of Maternal Antiretroviral Therapy After HIV Seroconversion in Pregnancy Effectively Prevents Vertical Transmission and Other Adverse Infant Outcomes
- Kavya G. Sundar(corresponding author),
- Lanbo Z. Yang,
- Mary C. Cambou,
- Ivana R.S. Varella,
- Marineide G. Melo,
- Suny Downstate Medical Center,
- Tulane University School of Medicine,
- David Geffen School of Medicine at UCLA,
- University of California Los Angeles,
- Rua Francisco Trein,
Research Output:
Contribution to journal
Article
Peer-review
Open access
Publication Information
Output type
Research Output:
Contribution to journal
Article
Peer-reviewOriginal language
EnglishPages from-to (Number of pages)
Pages 40-43 (4 pages)Journal (Volume, Issue Number)
Pediatric Infectious Disease Journal (Volume 44, Issue 1)Publication milestones
- Accepted/In press - 2024
- Published - 01/01/2025
Publication status
Published - 01/01/2025
ISSN
0891-3668Publication IDs
- Scopus: 85207156795
Abstract
From January 2008 to December 2018, 1348 HIV-exposed infants were born in Porto Alegre, Brazil; 18.8% had adverse infant outcomes (AIO) including vertical transmission (1.9%), stillbirth/neonatal death (4.0%) and loss to follow-up before HIV diagnosis (12.9%). Timing of maternal HIV diagnosis was not associated with AIO but absent antiretroviral therapy use was. Lack of maternal antiretroviral therapy use is a significant risk factor for AIO.
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Sustainable Development Goals
SDG 3 Good Health and Well