Is glucose-6-phosphate dehydrogenase deficiency more prevalent in Carrion's disease endemic areas in Latin America?
- Fernando Mazulis,
- Claudia Weilg,
- Carlos Alva-Urcia,
- ,
- Juana del Valle Mendoza(corresponding author)
- Universidad Peruana de Ciencias Aplicadas,
Research Output:
Contribution to journal
Letter
Peer-review
Open access
Publication Information
Output type
Research Output:
Contribution to journal
Letter
Peer-reviewOriginal language
EnglishPages from-to (Number of pages)
Pages 1079-1080 (2 pages)Journal (Volume, Issue Number)
Asian Pacific Journal of Tropical Medicine (Volume 8, Issue 12)Publication milestones
- Published - 01/12/2015
Publication status
Published - 01/12/2015
ISSN
1995-7645Publication IDs
- Scopus: 84952874547
Abstract
Glucose-6-phosphate dehydrogenase (G6PD) is a cytoplasmic enzyme with an important function in cell oxidative damage prevention. Erythrocytes have a predisposition towards oxidized environments due to their lack of mitochondria, giving G6PD a major role in its stability. G6PD deficiency (G6PDd) is the most common enzyme deficiency in humans; it affects approximately 400 million individuals worldwide. The overall G6PDd allele frequency across malaria endemic countries is estimated to be 8%, corresponding to approximately 220 million males and 133 million females. However, there are no reports on the prevalence of G6PDd in Andean communities where bartonellosis is prevalent.
Funding Details
Maria J. Pons has a postdoctoral fellowship from CONCYTEC/FONDECYT (grant number: CG05-2013-FONDECYT ).
FundersFunding numbers
CONCYTEC
CG05-2013-FONDECYT
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SDG 3 Good Health and Well