High prevalence and increased severity of norovirus mixed infections among children 12-24 months of age living in the suburban areas of Lima, Peru

Mara Zambruni
,
Giannina Luna
,
Maria Silva
,
Daniel G. Bausch
,
Fulton P. Rivera
,
Grace Velapatino

*Corresponding author for this work

University of Texas-Health Science Center at Houston
,
U.S. Naval Medical Research Unit No. 6
,
Tulane School of Public Health and Tropical Medicine
,
Medicina humana
,
Universidad Peruana Cayetano Heredia
,
School of Public Health, University of Texas

Research Output:

Contribution to journal

Article

Peer-review

Open access

Publication Information

Output type

Research Output:

Contribution to journal

Article

Peer-review

Original language

English

Article number

piv001

Pages from-to (Number of pages)

Pages 337-341 (5 pages)

Journal (Volume, Issue Number)

Journal of the Pediatric Infectious Diseases Society (Volume 5, Issue 3)

Publication milestones

Published - 01/09/2016

Publication status

Published - 01/09/2016

ISSN

2048-7193

Publication IDs

Scopus: 84995639932
PubMed: 27534674

Abstract

In an active diarrhea surveillance study of children aged 12-24 months in Lima, Peru, norovirus was the most common pathogen identified. The percentage of mixed (bacterial and noroviral) infections was significantly higher among norovirus-positive samples (53%) than among norovirus-negative samples (12%). The combination of norovirus with the most common bacterial pathogens was associated with increased clinical severity over that of either single-pathogen norovirus or single-pathogen bacterial infections.