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Helicobacter pylori detected in tap water of peruvian patients with gastric cancer

  • Miluska Castillo
    ,
  • Luis A. Bernabe
    ,
  • ,
  • Ivan Chavez
    ,
  • Eloy Ruiz
    ,
  • Fernando Barreda
  • Universidad Científica del Sur
    ,
  • Instituto Nacional de Enfermedades Neoplásicas
    ,
  • ,
  • A.C.Camargo Cancer Center
    ,
  • University of Michigan, Ann Arbor
Research Output:
Contribution to journal
Article
Peer-review

Open access

Publication Information

Output type

Research Output:
Contribution to journal
Article
Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 3193-3196 (4 pages)

Journal (Volume, Issue Number)

Asian Pacific Journal of Cancer Prevention (Volume 20, Issue 11)

Publication milestones

  • Published - 2019

Publication status

Published - 2019

ISSN

1513-7368

Publication IDs

  • Scopus: 85075585968
  • PubMed: 31759341

Abstract

Objective: To evaluate the correlation between the presence of H. pylori in paired samples of tap water and gastric cancer (GC) lesion in Lima city (Peru). Material and methods: Gastric tissue and tap-water samples were prospectively collected from 82 Gastric Cancer who lived in Lima. HspA and ureA genes were evaluated by qPCR in the samples. Results: The median age of patients with GC was 63 years, 52.4% were men and stage-II in 36.6%. A home-living time> 10 years was reported in 84.1% of patients. Boiling water treatment was indicated in 85.4% of cases. H. pylori was detected in 69.5% of gastric tissues and in 12.2% of analyzed tap-water. There was no differences in gastric infection rates among those with or without water contamination (70% vs. 69.4%, p=0.971). Conclusion & Impact: H. pylori was found in tap-water samples, however, detection rates were lower than in gastric cancer samples. Other sources of infection transmission should be investigated.

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Sustainable Development Goals

  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well