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Female orgasmic dysfunction and severe climacteric symptomatology in women aged 40 to 59years: an independent association from an analysis of a multicenter Latin American study

  • ,
  • Edward Mezones-Holguin
    ,
  • Juan E. Blümel
    ,
  • Moises Apolaya-Segura
    ,
  • German Barón
    ,
  • Emma Belzares
  • ,
  • Universidad San Ignacio de Loyola
    ,
  • Collaborative Group for Research of the Climacteric in Latin America (REDLINC
    ,
  • Facultad de Medicina de la Universidad de Chile
    ,
  • Universidad Católica de Santiago de Guayaquil
    ,
  • Universidad de San Martin de Porres
Research Output:
Contribution to journal
Article
Peer-review

Publication Information

Output type

Research Output:
Contribution to journal
Article
Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 654-663 (10 pages)

Journal (Volume, Issue Number)

Menopause (New York, N.Y.) (Volume 29, Issue 6)

Publication milestones

  • Published - 07/06/2022

Publication status

Published - 07/06/2022

ISSN

1072-3714

Publication IDs

  • Scopus: 85131771510
  • PubMed: 35674646

Abstract

Objective:To evaluate the association between the severity of climacteric symptoms (CS) and orgasmic dysfunction (OD), controlled by demographic, clinical, and partner variables.Methods:We carried out a secondary analysis of a multicenter Latin American cross-sectional study that surveyed sexually active women 40 to 59years old. We assessed CS (global, somatic, psychological, or urogenital domains) and OD. Also, we explored clinical variables and partner sexual conditions. We performed logistic regression models with nonparametric bootstrap resampling to estimate crude and adjusted odds ratios (aOR) with 95% confidence intervals (CI).Results:We included data of 5,391 women in the analysis. Regarding CS, 24.8%, 10.8%, 28.4%, and 32.9% had respectively severe symptoms according to total, somatic, psychological, and urogenital domain scores of the Menopause Rating Scale. OD was found in 25.4% of women. The adjusted model (including menopausal status and partner sexual dysfunction) showed that severe CS increased the odds of OD (aOR=2.77; 95% CI: 2.41-3.19 [total Menopause Rating Scale score]; aOR=1.65; 95% CI: 1.37-2.00 [somatic domain]; aOR=2.02; 95% CI: 1.76-2.32 [psychological domain] and aOR=3.89; 95% CI: 3.40-4.45 [urogenital]).Conclusions:Severe CS were associated with OD independently of demographic, clinical, and partner variables. Severe urogenital symptoms had the strongest association.

Funding Details

Financial disclosures/conflicts of interest: J.E.B. received funding from Grünenthal and FEMECOG. K.T. receives funding from Abbott, Procaps, and Aspen. The other authors have nothing to disclose. The authors would like to thank the women who participated in this study and Universidad San Ignacio de Loyola for funding the editorial editing services. Funding/support: This research did not receive any specific grant from funding agencies in the public, commercial, or non-for-profit sectors. P.C. is supported by the Sistema de Investigacion y Desarrollo and the Vice- Rectorado de Investigatión & Postgrado of the Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador, through grant No. SIU # 554-56 for the development of the project: “Evaluación de resultantes vinculadas a la salud de la mujer en etapa reproductiva y no reproductiva: Proyecto Omega III.” Also, Universidad San Ignacio de Loyola funded the editorial English editing services.
FundersFunding numbers
FEMECOG
-
Sistema de Investigacion y Desarrollo
-
Universidad Católica de Santiago de Guayaquil
554-56
Universidad San Ignacio de Loyola
-
Abbott Laboratories
-