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External validation of Finnish diabetes risk score (FINDRISC) and Latin American FINDRISC for screening of undiagnosed dysglycemia: Analysis in a Peruvian hospital health care workers sample

  • ,
  • Edward Mezones-Holguín
    ,
  • Rosa Agüero-Zamora
    ,
  • Lucy Damas-Casani
    ,
  • Becky Uriol-Llanos
    ,
  • Frank Espinoza-Morales
  • ,
  • Universidad San Ignacio de Loyola
    ,
  • Epi-gnosis Solutions
    ,
  • Universidad Nacional Federico Villarreal
    ,
  • Hospital María Auxiliadora
    ,
  • Red de Eficacia Clínica y Sanitaria (REDECS)
Research Output:
Contribution to journal
Article
Peer-review

Open access

Publication Information

Output type

Research Output:
Contribution to journal
Article
Peer-review

Original language

English

Article number

e0299674

Journal (Volume, Issue Number)

PLoS ONE (Volume 19, Issue 8 August)

Publication milestones

  • Published - 08/2024

Publication status

Published - 08/2024

Publication IDs

  • Scopus: 85200749883
  • PubMed: 39110713

Abstract

Aims To evaluate the external validity of Finnish diabetes risk score (FINDRISC) and Latin American FINDRISC (LAFINDRISC) for undiagnosed dysglycemia in hospital health care workers. Methods We carried out a cross-sectional study on health workers without a prior history of diabetes mellitus (DM). Undiagnosed dysglycemia (prediabetes or diabetes mellitus) was defined using fasting glucose and two-hour oral glucose tolerance test. LAFINDRISC is an adapted version of FINDRISC with different waist circumference cut-off points. We calculated the area under the receptor operational characteristic curve (AUROC) and explored the best cut-off point. Results We included 549 participants in the analysis. The frequency of undiagnosed dysglycemia was 17.8%. The AUROC of LAFINDRISC and FINDRISC were 71.5% and 69.2%; p = 0.007, respectively. The optimal cut-off for undiagnosed dysglycemiaaccording to Index Youden was ≥ 11 in LAFINDRISC (Sensitivity: 78.6%; Specificity: 51.7%) and ≥12 in FINDRISC (Sensitivity: 70.4%; Specificity: 53.9%) Conclusion The discriminative capacity of both questionnaires is good for the diagnosis of dysglycemia in the healthcare personnel of the María Auxiliadora hospital. The LAFINDRISC presented a small statistical difference, nontheless clinically similar, since there was no difference by age or sex. Further studies in the general population are required to validate these results.

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    SDG 3 Good Health and Well