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Evolution and management of the pediatric multi-systemic inflammatory syndrome associated with SARS CoV-2 infection in a pediatric ICU in Lima, Peru

Original title: Evolución y manejo del síndrome inflamatorio multisistémico pediátrico asociado a infección por SARSCoV-2 en una UCI pediátrica de Lima, Perú
  • Liliana Cieza-Yamunaqué
    ,
  • Ricardo Rodriguez-Portilla
    ,
  • Michael Baique-Sanchez
    ,
  • Edgar Coila-Paricahua
    ,
  • Claudia Guerra-Ríos
    ,
  • Patricia Llaque-Quiroz
Research Output: Contribution to journal Article Peer-review

Open access

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Publication Information

Output type

Research Output: Contribution to journal Article Peer-review

Original language

Spanish

Pages from-to (Number of pages)

Pages 262-266 (5 pages)

Journal (Volume, Issue Number)

Revista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo (Volume 14, Issue 3)

Publication milestones

  • Published - 11/2021

Publication status

Published - 11/2021

ISSN

2225-5109

Publication IDs

  • Scopus: 85122975055

Abstract

Background: Pediatric Multisystemic Inflammatory Syndrome (SIMP) associated with SARS CoV2 seriously affects children. Objective: To describe the symptoms, treatment and evolution of SIMP in patients of a reference Pediatric Intensive Care Unit (PICU). Findings: 18 children were identified with a mean age of 8.76 years, 50% male, all with a positive serological test. The most frequent manifestations were: fever (100%), respiratory distress (94%), abdominal pain (89%), elevated C-reactive protein (average 21.8), thrombocytopenia (50%), pathological chest X-ray (89%) and depressed myocardial contractility (61%). 72% required invasive mechanical ventilation (average 3 days) and catecholamines; 89% used corticosteroids plus immunoglobulins. The average stay in the PICU was 5.5 days. One patient died of intracerebral hemorrhage. Conclusions: SIMP in PICU is characterized by fever, respiratory distress, abdominal pain, elevated inflammatory markers, and myocardial depression. Requiring corticosteroids, immunoglobulin and ventilatory support; presenting intermediate stay and low mortality.