Epigenetic changes and microRNAs in the diagnosis and therapy of lung cancer

We know that our cells have gene expression patterns that can be on altered over and give rise lead to cancer. The epigenetic is the study of the changes in the gene expression without modifying the DNA sequence. The epigenetic and the genetic alterations are considered as two separate mechanisms involved in the onset and progression of the cancer. During the last decade have emphasized the field of the epigenetics to find applications in the diagnosis and therapy in this disease, along with microRNAs play an important role in the silencing of certain genes against certain conditions. In this review, we study and discussed the epigenetic changes and microRNAs that are notorious in the lung cancer and the importance of both in the early diagnosis of this disease and his therapy they are discussed.