Evidence based medicine perspective on long-term adverse effects of proton pump inhibitors
Original title: Efectos adversos a largo plazo de los inhibidores de la bomba de protones. Perspectiva desde la medicina basada en la evidencia
- Jaime A. Cardona-Ospina,
- Diego Alejandro Medina-Morales,
- ,
- Jorge E. Machado-Alba
- Universidad Tecnológica de Pereira
Research Output:
Contribution to journal
Review article
Peer-review
Open access
Publication Information
Output type
Research Output:
Contribution to journal
Review article
Peer-reviewOriginal language
SpanishPages from-to (Number of pages)
Pages 403-408 (6 pages)Journal (Volume, Issue Number)
Revista Colombiana de Gastroenterologia (Volume 31, Issue 4)Publication milestones
- Published - 2016
Publication status
Published - 2016
ISSN
0120-9957Publication IDs
- Scopus: 85013927551
Abstract
Proton pump inhibitors (PPIs) are the most effective gastric secretion suppressors and are among the most widely prescribed and widely available drugs in the United States of America. In some cases they are prescribed without justification. In recent years, concerns have arisen over reports of major adverse reactions related to the use of PPIs. However, the quality of the evidence has not been conclusive, and in some cases the magnitude of the risk has not been clinically significant. The objective of this review is to present the available evidence regarding the most important adverse events related to PPIs.