Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review
Original title: Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum: A case-based review
- Julio Alejandro Cerna-López,
- Paul J. Tejada-Llacsa(corresponding author),
- Fiorella Andrea de Jesús Valle-Farfán,
- Graciela S. Alarcón,
- ,
- Víctor R. Pimentel-Quiroz
- Hospital Guillermo Almenara Irigoyen,
- Universidad Peruana Cayetano Heredia,
- University of Alabama at Birmingham School of Medicine,
- ,
- Universidad Científica del Sur
Research Output:
Contribution to journal
Article
Peer-reviewPublication Information
Output type
Research Output:
Contribution to journal
Article
Peer-reviewOriginal language
EnglishPages from-to (Number of pages)
Pages 277-282 (6 pages)Journal (Volume, Issue Number)
Revista Colombiana de Reumatologia (Volume 30, Issue 3)Publication milestones
- Accepted/In press - 2021
- Published - 01/07/2023
Publication status
Published - 01/07/2023
ISSN
0121-8123Publication IDs
- Scopus: 85111033501
Abstract
Clinically amyopathic dermatomyositis (CADM) is associated with antibodies directed against the protein encoded by the melanoma differentiation-associated gene 5 (MDA5). CADM patients have an increased risk of developing rapidly progressive interstitial lung disease (RP-ILD) and spontaneous pneumomediastinum. Two Peruvian cases of RP-ILD-associated CADM with spontaneous pneumomediastinum are presented, one of them was anti-MDA5 antibody positive. To our knowledge, this is the first report of anti-MDA5-associated CADM in the Peruvian population.
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