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COVID-19 - Recent advancements in identifying novel vaccine candidates and current status of upcoming SARS-CoV-2 vaccines

  • Mohd Iqbal Yatoo
    ,
  • Zeenat Hamid
    ,
  • Oveas Rafiq Parray
    ,
  • Aasim Habib Wani
    ,
  • Abrar Ul Haq
    ,
  • Archana Saxena
  • Sher-E-Kashmir University of Agricultural Sciences and Technology of Kashmir Shalimar
    ,
  • University of Kashmir
    ,
  • ICAR-Indian Veterinary Research Institute
    ,
  • Up Pandit Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan (DUVASU)
    ,
  • Tribhuvan University Teaching Hospital
    ,
  • Johns Hopkins Aramco Healthcare
Research Output:
Contribution to journal
Review article
Peer-review

Open access

Publication Information

Output type

Research Output:
Contribution to journal
Review article
Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 2891-2904 (14 pages)

Journal (Volume, Issue Number)

Human Vaccines and Immunotherapeutics (Volume 16, Issue 12)

Publication milestones

  • Published - 2020

Publication status

Published - 2020

ISSN

2164-5515

Publication IDs

  • Scopus: 85088536358
  • PubMed: 32703064

Abstract

The COVID-19 pandemic caused by SARS-CoV-2 has spread rapidly. To date, countries have relied on the prevention of the disease through isolation, quarantine, and clinical care of affected individuals. However, studies on the roles of asymptomatic and mildly infected subjects in disease transmission, use of antiviral drugs, and vaccination of the general population will be very important for mitigating the effects of the eventual return of this pandemic. Initial investigations are ongoing to evaluate antigenic structures of SARS-CoV-2 and the immunogenicity of vaccine candidates. There also is a need to comprehensively compile the details of previous studies on SARS-related vaccines that can be extrapolated to identify potent vaccine targets for developing COVID-19 vaccines. This review aims to analyze previous studies, current status, and future possibilities for producing SARS-CoV-2 vaccines.

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Sustainable Development Goals

  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well