Biomaterials for Reconstructive Treatment of Peri-Implantitis

Peri-implantitis is a pathological condition affecting the tissues surrounding dental implants, marked by inflammation of the peri-implant connective tissue and progressive loss of supporting bone. With strong evidence indicating a bacterial origin, effective treatment approaches should employ anti-infective strategies. Due to the limited success of non-surgical approaches, surgical therapy—offering direct access to contaminated implant surfaces—is often necessary. This narrative review aims to summarize the available biomaterials and their effectiveness in the reconstructive management of peri-implantitis. Reconstructive techniques should be employed in cases with contained defect morphology. While the ideal biomaterial for bone regeneration in these cases remains uncertain, bone substitutes with low resorption rates tend to yield more favorable outcomes compared to autogenous bone. Comparative studies have not demonstrated clear clinical advantages from the adjunctive use of barrier membranes. Current evidence also does not support definitive conclusions regarding the benefits of adding biologics to reconstructive treatments.