MicroRNA dysregulation in cancer: A therapeutic and diagnostic approach
- Luis Tume(corresponding author),
- Carlos Cisneros,
- Josmell Sevillano,
- Romina Pacheco-Tapia,
- Daniel Matos,
- Universidad Peruana Cayetano Heredia,
- Universidad Nacional de Piura,
- Universidad Científica del Sur,
- ,
- Universidad Privada del Norte,
- Carrera de Psicología
Research Output:
Contribution to journal
Short survey
Research
Peer-reviewOpen access
Publication Information
Output type
Research Output:
Contribution to journal
Short survey
Research
Peer-reviewOriginal language
EnglishPages from-to (Number of pages)
Pages 298-304 (7 pages)Journal (Volume, Issue Number)
Gaceta Mexicana de Oncologia (Volume 15, Issue 5)Publication milestones
- Published - 01/09/2016
Publication status
Published - 01/09/2016
ISSN
1665-9201Publication IDs
- Scopus: 84994429454
Abstract
Cancer is one of the leading causes of death worldwide, and in many cases this is due to late detection of the disease, which complicates its treatment. MicroRNAs are short non-coding RNA sequences of ∼19-23 nucleotides that play a critical role in multiple cellular processes through post-transcriptional and translational regulation of specific genes, and an alteration in this regulatory mechanism leads to cancer. In this review, we discuss microRNA dysregulation in cancer, and propose applications of these small molecules in the treatment and diagnosis of cancer.
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- SDG 3 Good Health and Well
