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MicroRNA dysregulation in cancer: A therapeutic and diagnostic approach

  • Luis Tume(corresponding author)
    ,
  • Carlos Cisneros
    ,
  • Josmell Sevillano
    ,
  • Romina Pacheco-Tapia
    ,
  • Daniel Matos
    ,
*Corresponding author for this work
  • Universidad Peruana Cayetano Heredia
    ,
  • Universidad Nacional de Piura
    ,
  • Universidad Científica del Sur
    ,
  • ,
  • Universidad Privada del Norte
    ,
  • Carrera de Psicología
Research Output:
Contribution to journal
Short survey
Peer-review

Open access

Publication Information

Output type

Research Output:
Contribution to journal
Short survey
Peer-review

Original language

English

Pages from-to (Number of pages)

Pages 298-304 (7 pages)

Journal (Volume, Issue Number)

Gaceta Mexicana de Oncologia (Volume 15, Issue 5)

Publication milestones

  • Published - 01/09/2016

Publication status

Published - 01/09/2016

ISSN

1665-9201

Publication IDs

  • Scopus: 84994429454

Abstract

Cancer is one of the leading causes of death worldwide, and in many cases this is due to late detection of the disease, which complicates its treatment. MicroRNAs are short non-coding RNA sequences of ∼19-23 nucleotides that play a critical role in multiple cellular processes through post-transcriptional and translational regulation of specific genes, and an alteration in this regulatory mechanism leads to cancer. In this review, we discuss microRNA dysregulation in cancer, and propose applications of these small molecules in the treatment and diagnosis of cancer.

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Sustainable Development Goals

  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well