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Carrion's disease: An eradicable illness?

  • ,
  • bUniversidad Peruana de Ciencias Aplicadas
    ,
  • cUniversitat de Barcelona
Research Output: Contribution to journal Comment/debate

Open access

Publication Information

Output type

Research Output: Contribution to journal Comment/debate

Original language

English

Article number

105

Journal (Volume, Issue Number)

Infectious Diseases of Poverty (Volume 5, Issue 1)

Publication milestones

  • Published
    - 01/12/2016

Publication status

Published
- 01/12/2016

ISSN

2095-5162

External Publication IDs

  • Scopus: 85000473331
  • PubMed: 27903286

Abstract

Carrion's disease is a neglected tropical disease caused by Bartonella bacilliformis, a vector-borne pathogen restricted to the Andean valleys of Peru, Ecuador and Colombia. Carrion's disease is a biphasic illness; in the acute phase the case-fatality rate can be as high as 88 %, related to high parasitemia, arriving to almost all erythrocytes, and secondary bacterial infections close related with the development of transient immunosuppression in the earlier illness phases. In addition, there are an undefined number of asymptomatic carriers that are reservoirs of the etiological agent of Carrion's disease in endemic areas, they make take into account due to they are the perpetuators of this disease. The actual scenario of Carrion's disease, in which the illness is arriving to new areas, due to the expansion of the vector's distribution, suggests that now may be a crucial time to design a strategy focusing on its elimination.

Funding Details

MJP has a postdoctoral fellowship from CONCYTEC/FONDECYT [grant number: CG05-2013-FONDECYT] and Programa Nacional de Innovación para la Competitividad y Productividad (Innóvate Perú), under the contract 117-PNICP-PIAP-2015 Perú. CG has a PhD fellowship of the ISCIII [FI12/00561]. JR has a fellowship from the program I3, of the ISCIII [grant number: CES11/012].
FundersFunding numbers
Programa Nacional de Innovación para la Competitividad y Productividad
117-PNICP-PIAP-2015
ISCIII
CES11/012
CONCYTEC
CG05-2013-FONDECYT

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  • SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well