A systematic review of population-based studies on lipid profiles in latin america and the caribbean
- Rodrigo M. Carrillo-Larco,
- C. Joel Benites-Moya,
- Cecilia Anza-Ramirez,
- Leonardo Albitres-Flores,
- Diana Sánchez-Velazco,
- Niels Pacheco-Barrios
- Universidad Peruana Cayetano Heredia,
- Universidad Católica los Ángeles de Chimbote,
- Imperial College London,
- Universidad Nacional de Trujillo,
- Sociedad Científica de Estudiantes de Medicina de la Universidad Nacional de Trujillo,
Open access
Publication Information
Output type
Original language
EnglishArticle number
e57980Pages from-to (Number of pages)
Pages 1-13 (13 pages)Journal (Volume, Issue Number)
eLife (Volume 9)Publication milestones
- Published - 08/2020
Publication status
Publication IDs
- Scopus: 85089634432
- PubMed: 32807300
Abstract
We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC.