Genetics and Neurocognition in Latinos With and Without Parkinson’s Disease

<b>GENERAL OBJECTIVE:<br/></b>To establish a clinical–molecular registry and a centralized database of Latino individuals, with and without Parkinson’s disease (PD), in order to investigate genetic and risk factors associated with cognitive decline in this population.<br/><b>SPECIFIC OBJECTIVES:<br/></b>To increase the representation of Latinos in research on neurodegenerative diseases such as PD, Alzheimer’s disease, and Alzheimer’s disease–related dementias (ADRD).<br/>To collect demographic, clinical, cognitive, and genetic data, as well as biological samples (blood), from at least 1,500 Hispanic participants.<br/>To identify specific risk factors and molecular mechanisms involved in cognitive decline.