Prompt Initiation of Maternal Antiretroviral Therapy After HIV Seroconversion in Pregnancy Effectively Prevents Vertical Transmission and Other Adverse Infant Outcomes

Kavya G. Sundar, Lanbo Z. Yang, Mary C. Cambou, Ivana R.S. Varella, Marineide G. Melo, Eddy R. Segura, Ângela P. Ziegler, Breno R. Santos, Karin Nielsen-Saines

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

Resumen

From January 2008 to December 2018, 1348 HIV-exposed infants were born in Porto Alegre, Brazil; 18.8% had adverse infant outcomes (AIO) including vertical transmission (1.9%), stillbirth/neonatal death (4.0%) and loss to follow-up before HIV diagnosis (12.9%). Timing of maternal HIV diagnosis was not associated with AIO but absent antiretroviral therapy use was. Lack of maternal antiretroviral therapy use is a significant risk factor for AIO.

Idioma originalInglés
Número de artículo10.1097/INF.0000000000004562
PublicaciónPediatric Infectious Disease Journal
DOI
EstadoAceptada/en prensa - 2024

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