TY - JOUR
T1 - Optimal definitions for abdominal obesity and the metabolic syndrome in Andean Hispanics
T2 - The PREVENCION study
AU - Medina-Lezama, Josefina
AU - Pastorius, Catherine A.
AU - Zea-Diaz, Humberto
AU - Bernabe-Ortiz, Antonio
AU - Corrales-Medina, Fernando
AU - Morey-Vargas, Oscar Leopoldo
AU - Chirinos, Diana Andrea
AU - Mũnoz-Atahualpa, Edgar
AU - Chirinos-Pacheco, Julio
AU - Chirinos, Julio Alonso
PY - 2010/6
Y1 - 2010/6
N2 - OBJECTIVE - We aimed to establish optimal definitions for abdominal obesity and metabolic syndrome (MetS) among Andean adults. RESEARCH DESIGN AND METHODS - Among 1,448 Andean adults, we assessed the relationship between waist circumference and subclinical vascular disease assessed by carotid intima-media thickness (cIMT) and manifest cardiovascular disease (M-CVD). RESULTS - Optimal waist circumference cutoffs to classify individuals with abnormal cIMT or M-CVD were >97 and >87 cm in men and women, respectively. With these cutoffs, there was substantial disagreement between the original American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI) and the recently updated MetS definition, particularly among men (κ = 0.85). Subjects with MetS identified by the updated definition but not meeting the original AHA/NHLBI MetS criteria demonstrated significantly increased cIMT (P < 0.001) compared with subjects who did not meet the MetS criteria by either definition. CONCLUSIONS - Our findings support the use of ethnic-specific waist circumference cutoffs and the updated MetS definition in Andean adults.
AB - OBJECTIVE - We aimed to establish optimal definitions for abdominal obesity and metabolic syndrome (MetS) among Andean adults. RESEARCH DESIGN AND METHODS - Among 1,448 Andean adults, we assessed the relationship between waist circumference and subclinical vascular disease assessed by carotid intima-media thickness (cIMT) and manifest cardiovascular disease (M-CVD). RESULTS - Optimal waist circumference cutoffs to classify individuals with abnormal cIMT or M-CVD were >97 and >87 cm in men and women, respectively. With these cutoffs, there was substantial disagreement between the original American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI) and the recently updated MetS definition, particularly among men (κ = 0.85). Subjects with MetS identified by the updated definition but not meeting the original AHA/NHLBI MetS criteria demonstrated significantly increased cIMT (P < 0.001) compared with subjects who did not meet the MetS criteria by either definition. CONCLUSIONS - Our findings support the use of ethnic-specific waist circumference cutoffs and the updated MetS definition in Andean adults.
UR - http://www.scopus.com/inward/record.url?scp=77956075591&partnerID=8YFLogxK
U2 - 10.2337/dc09-2353
DO - 10.2337/dc09-2353
M3 - Artículo
C2 - 20200303
AN - SCOPUS:77956075591
SN - 0149-5992
VL - 33
SP - 1385
EP - 1388
JO - Diabetes Care
JF - Diabetes Care
IS - 6
ER -
