TY - JOUR
T1 - Molecular characterization of the integrons in Shigella strains isolated from patients with traveler's diarrhea
AU - Navia, M. M.
AU - Ruiz, J.
AU - Vila, J.
N1 - Funding Information:
This work was supported by grant FIS02/0353 from the Fondo de Investigaciones Sanitarias.
PY - 2004/3
Y1 - 2004/3
N2 - The prevalence and characterization of Class 1 integrons has been performed in eighty three strains of Shigella spp., isolated between 1995 and 2000 from patients with traveler's diarrhea. A low prevalence (13.25%) was recorded. Nine different integrons were found among 11 multiresistant strains, with a total of 10 different gene cassettes encoding for resistance to trimethoprim (dfrA1, dfrA5, dfrA7, dfrA12, and dfrA15), aminoglycosides (aadA1a and aadA2), β-lactam antibiotics (oxa2) or ORF with unknown function (orfD and orfF). A high prevalence of dfr and aad gene cassettes was observed. The low incidence of Class 1 integrons observed in this study is in contrast with the known facility that the Shigella genus has to gain and transfer plasmids.
AB - The prevalence and characterization of Class 1 integrons has been performed in eighty three strains of Shigella spp., isolated between 1995 and 2000 from patients with traveler's diarrhea. A low prevalence (13.25%) was recorded. Nine different integrons were found among 11 multiresistant strains, with a total of 10 different gene cassettes encoding for resistance to trimethoprim (dfrA1, dfrA5, dfrA7, dfrA12, and dfrA15), aminoglycosides (aadA1a and aadA2), β-lactam antibiotics (oxa2) or ORF with unknown function (orfD and orfF). A high prevalence of dfr and aad gene cassettes was observed. The low incidence of Class 1 integrons observed in this study is in contrast with the known facility that the Shigella genus has to gain and transfer plasmids.
KW - Antibiotic resistance
KW - Gene cassettes
KW - Genetic elements
UR - http://www.scopus.com/inward/record.url?scp=1542614037&partnerID=8YFLogxK
U2 - 10.1016/j.diagmicrobio.2003.10.007
DO - 10.1016/j.diagmicrobio.2003.10.007
M3 - Artículo
C2 - 15023426
AN - SCOPUS:1542614037
SN - 0732-8893
VL - 48
SP - 175
EP - 179
JO - Diagnostic Microbiology and Infectious Disease
JF - Diagnostic Microbiology and Infectious Disease
IS - 3
ER -
