Is glucose-6-phosphate dehydrogenase deficiency more prevalent in Carrion's disease endemic areas in Latin America?

Fernando Mazulis, Claudia Weilg, Carlos Alva-Urcia, Maria J. Pons, Juana del Valle Mendoza

Producción científica: Contribución a una revistaCartarevisión exhaustiva

Resumen

Glucose-6-phosphate dehydrogenase (G6PD) is a cytoplasmic enzyme with an important function in cell oxidative damage prevention. Erythrocytes have a predisposition towards oxidized environments due to their lack of mitochondria, giving G6PD a major role in its stability. G6PD deficiency (G6PDd) is the most common enzyme deficiency in humans; it affects approximately 400 million individuals worldwide. The overall G6PDd allele frequency across malaria endemic countries is estimated to be 8%, corresponding to approximately 220 million males and 133 million females. However, there are no reports on the prevalence of G6PDd in Andean communities where bartonellosis is prevalent.

Idioma originalInglés
Páginas (desde-hasta)1079-1080
Número de páginas2
PublicaciónAsian Pacific Journal of Tropical Medicine
Volumen8
N.º12
DOI
EstadoPublicada - 1 dic. 2015

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