High rates of extensively drug-resistant Acinetobacter baumannii in a Peruvian hospital 2013–2019

Rodrigo Samuel Barrientos-Yong, Bryan Andrei Hinojosa-Salas, Percy Genaro Salas-Ponce, Eddie Angles, Joaquim Ruiz, Maria J. Pons

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

1 Cita (Scopus)

Resumen

Multidrug-resistant (MDR) Acinetobacter baumannii has become a major concern of hospital care. The objective of the study was to evaluate the evolution of antimicrobial resistance of A. baumannii in a Peruvian hospital from 2013 to 2019. A total of 993 A. baumannii clinical isolates were recovered. Antimicrobial resistance levels were extremely high, except for colistin. Among the remaining antibacterial agents, ampicillin plus sulbactam (AMS) was the most active (71.4% of resistance), with resistance levels to the remaining agents ranging from 75.9% to amikacin to 99.2% to ertapenem. The presence of significant differences was observed in extensively drug-resistant (XDR) A. baumannii according to samples origin. No association was observed between MDR or XDR isolates and seasonality. An impressive rate of XDR A. baumannii isolates was found, including a growing number of only-colistin-susceptible isolates highlighting the urgent need for new therapeutic alternatives.

Idioma originalInglés
Páginas (desde-hasta)248-255
Número de páginas8
PublicaciónTropical Doctor
Volumen53
N.º2
DOI
EstadoPublicada - abr. 2023

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