High rates of extensively drug-resistant Acinetobacter baumannii in a Peruvian hospital 2013–2019

Rodrigo Samuel Barrientos-Yong; Bryan Andrei Hinojosa-Salas; Percy Genaro Salas-Ponce; Eddie Angles; Joaquim Ruiz; Maria J. Pons

doi:10.1177/00494755221142939

High rates of extensively drug-resistant Acinetobacter baumannii in a Peruvian hospital 2013–2019

Rodrigo Samuel Barrientos-Yong, Bryan Andrei Hinojosa-Salas, Percy Genaro Salas-Ponce, Eddie Angles, Joaquim Ruiz, Maria J. Pons

Medicina humana

Resultado de la investigación: Contribución a una revista › Artículo › revisión exhaustiva

Resumen

Multidrug-resistant (MDR) Acinetobacter baumannii has become a major concern of hospital care. The objective of the study was to evaluate the evolution of antimicrobial resistance of A. baumannii in a Peruvian hospital from 2013 to 2019. A total of 993 A. baumannii clinical isolates were recovered. Antimicrobial resistance levels were extremely high, except for colistin. Among the remaining antibacterial agents, ampicillin plus sulbactam (AMS) was the most active (71.4% of resistance), with resistance levels to the remaining agents ranging from 75.9% to amikacin to 99.2% to ertapenem. The presence of significant differences was observed in extensively drug-resistant (XDR) A. baumannii according to samples origin. No association was observed between MDR or XDR isolates and seasonality. An impressive rate of XDR A. baumannii isolates was found, including a growing number of only-colistin-susceptible isolates highlighting the urgent need for new therapeutic alternatives.

Idioma original	Inglés
Publicación	Tropical Doctor
DOI	https://doi.org/10.1177/00494755221142939
Estado	Aceptada/en prensa - 2022

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

Acceder al documento

10.1177/00494755221142939

Otros archivos y enlaces

Enlace a la publicación en Scopus

Citar esto

@article{7118eab36bef4b28974b9c6427bd27d8,

title = "High rates of extensively drug-resistant Acinetobacter baumannii in a Peruvian hospital 2013–2019",

abstract = "Multidrug-resistant (MDR) Acinetobacter baumannii has become a major concern of hospital care. The objective of the study was to evaluate the evolution of antimicrobial resistance of A. baumannii in a Peruvian hospital from 2013 to 2019. A total of 993 A. baumannii clinical isolates were recovered. Antimicrobial resistance levels were extremely high, except for colistin. Among the remaining antibacterial agents, ampicillin plus sulbactam (AMS) was the most active (71.4% of resistance), with resistance levels to the remaining agents ranging from 75.9% to amikacin to 99.2% to ertapenem. The presence of significant differences was observed in extensively drug-resistant (XDR) A. baumannii according to samples origin. No association was observed between MDR or XDR isolates and seasonality. An impressive rate of XDR A. baumannii isolates was found, including a growing number of only-colistin-susceptible isolates highlighting the urgent need for new therapeutic alternatives.",

keywords = "Acinetobacter baumannii, Latin America, Multidrug-resistant, extensively drug-resistant",

author = "Barrientos-Yong, {Rodrigo Samuel} and Hinojosa-Salas, {Bryan Andrei} and Salas-Ponce, {Percy Genaro} and Eddie Angles and Joaquim Ruiz and Pons, {Maria J.}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2022.",

year = "2022",

doi = "10.1177/00494755221142939",

language = "Ingl{\'e}s",

journal = "Tropical Doctor",

issn = "0049-4755",

publisher = "SAGE Publications Ltd",

}

TY - JOUR

T1 - High rates of extensively drug-resistant Acinetobacter baumannii in a Peruvian hospital 2013–2019

AU - Barrientos-Yong, Rodrigo Samuel

AU - Hinojosa-Salas, Bryan Andrei

AU - Salas-Ponce, Percy Genaro

AU - Angles, Eddie

AU - Ruiz, Joaquim

AU - Pons, Maria J.

N1 - Publisher Copyright: © The Author(s) 2022.

PY - 2022

Y1 - 2022

N2 - Multidrug-resistant (MDR) Acinetobacter baumannii has become a major concern of hospital care. The objective of the study was to evaluate the evolution of antimicrobial resistance of A. baumannii in a Peruvian hospital from 2013 to 2019. A total of 993 A. baumannii clinical isolates were recovered. Antimicrobial resistance levels were extremely high, except for colistin. Among the remaining antibacterial agents, ampicillin plus sulbactam (AMS) was the most active (71.4% of resistance), with resistance levels to the remaining agents ranging from 75.9% to amikacin to 99.2% to ertapenem. The presence of significant differences was observed in extensively drug-resistant (XDR) A. baumannii according to samples origin. No association was observed between MDR or XDR isolates and seasonality. An impressive rate of XDR A. baumannii isolates was found, including a growing number of only-colistin-susceptible isolates highlighting the urgent need for new therapeutic alternatives.

AB - Multidrug-resistant (MDR) Acinetobacter baumannii has become a major concern of hospital care. The objective of the study was to evaluate the evolution of antimicrobial resistance of A. baumannii in a Peruvian hospital from 2013 to 2019. A total of 993 A. baumannii clinical isolates were recovered. Antimicrobial resistance levels were extremely high, except for colistin. Among the remaining antibacterial agents, ampicillin plus sulbactam (AMS) was the most active (71.4% of resistance), with resistance levels to the remaining agents ranging from 75.9% to amikacin to 99.2% to ertapenem. The presence of significant differences was observed in extensively drug-resistant (XDR) A. baumannii according to samples origin. No association was observed between MDR or XDR isolates and seasonality. An impressive rate of XDR A. baumannii isolates was found, including a growing number of only-colistin-susceptible isolates highlighting the urgent need for new therapeutic alternatives.

KW - Acinetobacter baumannii

KW - Latin America

KW - Multidrug-resistant

KW - extensively drug-resistant

UR - http://www.scopus.com/inward/record.url?scp=85144228724&partnerID=8YFLogxK

U2 - 10.1177/00494755221142939

DO - 10.1177/00494755221142939

M3 - Artículo

C2 - 36518018

AN - SCOPUS:85144228724

SN - 0049-4755

JO - Tropical Doctor

JF - Tropical Doctor

ER -

High rates of extensively drug-resistant Acinetobacter baumannii in a Peruvian hospital 2013–2019

Resumen

ODS de las Naciones Unidas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto