TY - JOUR
T1 - Etiology of diarrhea in children younger than 5 years of age admitted in a rural hospital of Southern Mozambique
AU - Mandomando, Inácio M.
AU - Macete, Eusébio V.
AU - Ruiz, Joaquim
AU - Sanz, Sergi
AU - Abacassamo, Fatima
AU - Vallès, Xavier
AU - Sacarlal, Jahit
AU - Navia, Margarita M.
AU - Vila, Jordi
AU - Alonso, Pedro L.
AU - Gascon, Joaquim
PY - 2007/3
Y1 - 2007/3
N2 - Diarrhea is one of the main causes of morbidity and mortality among children in sub-Saharan Africa and one of the main causes of hospital admissions in rural areas. Stool samples were collected from 529 children admitted with diarrhea to the Manhiça District Hospital (September 2000 to September 2001) and processed to detect bacterial enteropathogens, parasites, and virus. Diarrheagenic Escherichia coli, isolated from 120 samples (22.6%; enteropathogenic [9.6%], enterotoxigenic [6.8%], enteroaggregative [4.3%], and verotoxigenic [1.9%]) was the most frequently isolated pathogen, followed by Ascaris lumbricoides (9.3%). Others detected included Salmonella spp. and Giardia lamblia (2.5% each) and Campylobacter spp. (1.7%). A. lumbricoides (92% versus 8%; P < 0.001) and Strongyloides stercolaris (100% versus 0%; P = 0.008) were most frequently isolated in children older than 12 months of age. Resistance to trimethoprim-sulphametoxazole and ampicillin was high. Etiologic data on diarrheal diseases and susceptibility patterns of diarrheal pathogens are important tools for clinical management and control strategic planning.
AB - Diarrhea is one of the main causes of morbidity and mortality among children in sub-Saharan Africa and one of the main causes of hospital admissions in rural areas. Stool samples were collected from 529 children admitted with diarrhea to the Manhiça District Hospital (September 2000 to September 2001) and processed to detect bacterial enteropathogens, parasites, and virus. Diarrheagenic Escherichia coli, isolated from 120 samples (22.6%; enteropathogenic [9.6%], enterotoxigenic [6.8%], enteroaggregative [4.3%], and verotoxigenic [1.9%]) was the most frequently isolated pathogen, followed by Ascaris lumbricoides (9.3%). Others detected included Salmonella spp. and Giardia lamblia (2.5% each) and Campylobacter spp. (1.7%). A. lumbricoides (92% versus 8%; P < 0.001) and Strongyloides stercolaris (100% versus 0%; P = 0.008) were most frequently isolated in children older than 12 months of age. Resistance to trimethoprim-sulphametoxazole and ampicillin was high. Etiologic data on diarrheal diseases and susceptibility patterns of diarrheal pathogens are important tools for clinical management and control strategic planning.
UR - http://www.scopus.com/inward/record.url?scp=34247149807&partnerID=8YFLogxK
U2 - 10.4269/ajtmh.2007.76.522
DO - 10.4269/ajtmh.2007.76.522
M3 - Artículo
C2 - 17360878
AN - SCOPUS:34247149807
SN - 0002-9637
VL - 76
SP - 522
EP - 527
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 3
ER -