TY - JOUR
T1 - Development and formulation of the experimental dentifrice based on passiflora mollissima (Tumbo) with and without fluoride anion
T2 - Antibacterial activity on seven antimicrobial strains
AU - Mayta-Tovalino, Frank
AU - Gamboa, Eloy
AU - Sánchez, Richard
AU - Rios, Jorge
AU - Medina, Ramín
AU - García, Martín
AU - Asencios, Jhonn
N1 - Publisher Copyright:
© 2019 Frank Mayta-Tovalino et al.
PY - 2019
Y1 - 2019
N2 - Objectives. To develop and formulate a new experimental dentifrice with and without fluoride based on the peel and the fruit of the Passiflora mollissima (tumbo) and also to evaluate its antimicrobial activity against seven bacterial strains. Methods. The sample was calculated using the mean comparison formula, obtaining wells (n = 12) for each of the strains evaluated: S. mutans, E. faecalis, Actinomyces, Lactobacillus, C. albicans, S. sanguinis, and S. oralis. The antibacterial activity of the dentifrice was evaluated by the direct contact technique. Results. It was found that the highest antimicrobial activity was only present in pulp-based dentifrices against strains of S. mutans 21.0 ± 1.8, E. faecalis 16.3 ± 3.9, Actinomyces 22.1 ± 1.3, and Lactobacillus 21.0 ± 1.3. However, in comparison with other strains such as C. albicans, S. sanguinis, and S. oralis, the peel-based dendrifrice of Passiflora mollissima obtained the highest antimicrobial activity. Conclusion. The experimental dentifrice based on Passiflora mollissima had an antibacterial effect against the seven microbial strains during the first 24 and 48 hours.
AB - Objectives. To develop and formulate a new experimental dentifrice with and without fluoride based on the peel and the fruit of the Passiflora mollissima (tumbo) and also to evaluate its antimicrobial activity against seven bacterial strains. Methods. The sample was calculated using the mean comparison formula, obtaining wells (n = 12) for each of the strains evaluated: S. mutans, E. faecalis, Actinomyces, Lactobacillus, C. albicans, S. sanguinis, and S. oralis. The antibacterial activity of the dentifrice was evaluated by the direct contact technique. Results. It was found that the highest antimicrobial activity was only present in pulp-based dentifrices against strains of S. mutans 21.0 ± 1.8, E. faecalis 16.3 ± 3.9, Actinomyces 22.1 ± 1.3, and Lactobacillus 21.0 ± 1.3. However, in comparison with other strains such as C. albicans, S. sanguinis, and S. oralis, the peel-based dendrifrice of Passiflora mollissima obtained the highest antimicrobial activity. Conclusion. The experimental dentifrice based on Passiflora mollissima had an antibacterial effect against the seven microbial strains during the first 24 and 48 hours.
UR - http://www.scopus.com/inward/record.url?scp=85068183475&partnerID=8YFLogxK
U2 - 10.1155/2019/9056590
DO - 10.1155/2019/9056590
M3 - Artículo
AN - SCOPUS:85068183475
SN - 1687-8728
VL - 2019
JO - International Journal of Dentistry
JF - International Journal of Dentistry
M1 - 9056590
ER -