TY - JOUR
T1 - Rapidly progressive interstitial lung disease-associated hypomyopathic dermatomyositis complicated with pneumomediastinum
T2 - A case-based review
AU - Cerna-López, Julio Alejandro
AU - Tejada-Llacsa, Paul J.
AU - Valle-Farfán, Fiorella Andrea de Jesús
AU - Alarcón, Graciela S.
AU - Ugarte-Gil, Manuel F.
AU - Pimentel-Quiroz, Víctor R.
N1 - Publisher Copyright:
© 2021 Asociación Colombiana de Reumatología
PY - 2023/7/1
Y1 - 2023/7/1
N2 - Clinically amyopathic dermatomyositis (CADM) is associated with antibodies directed against the protein encoded by the melanoma differentiation-associated gene 5 (MDA5). CADM patients have an increased risk of developing rapidly progressive interstitial lung disease (RP-ILD) and spontaneous pneumomediastinum. Two Peruvian cases of RP-ILD-associated CADM with spontaneous pneumomediastinum are presented, one of them was anti-MDA5 antibody positive. To our knowledge, this is the first report of anti-MDA5-associated CADM in the Peruvian population.
AB - Clinically amyopathic dermatomyositis (CADM) is associated with antibodies directed against the protein encoded by the melanoma differentiation-associated gene 5 (MDA5). CADM patients have an increased risk of developing rapidly progressive interstitial lung disease (RP-ILD) and spontaneous pneumomediastinum. Two Peruvian cases of RP-ILD-associated CADM with spontaneous pneumomediastinum are presented, one of them was anti-MDA5 antibody positive. To our knowledge, this is the first report of anti-MDA5-associated CADM in the Peruvian population.
KW - Anti-MDA5 antibodies
KW - Clinically amyopathic dermatomyositis
KW - Spontaneous pneumomediastinum
UR - http://www.scopus.com/inward/record.url?scp=85111033501&partnerID=8YFLogxK
U2 - 10.1016/j.rcreu.2021.06.001
DO - 10.1016/j.rcreu.2021.06.001
M3 - Artículo
AN - SCOPUS:85111033501
SN - 0121-8123
VL - 30
SP - 277
EP - 282
JO - Revista Colombiana de Reumatologia
JF - Revista Colombiana de Reumatologia
IS - 3
ER -