Análisis in silico de variantes transferibles de QepA y de bombas cromosomales de eflujo relacionadas

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

4 Citas (Scopus)

Resumen

Objectives. The present study aimed to detect the presence of undescribed QepA variants in GenBank records. Material and methods. The DNA and amino acid sequences of QepA1 were compared with what is present in GenBank. Only annealings with a >80% identity were considered. No synthetic or partial sequences were included in the analyses. Results. The results showed the presence of 10 different QepA variants, 6 of them which were previously non-des-ignated as specific allelic variants. In addition, high identity levels with chromosomal MSF efflux pumps belonging to microorganisms of the Pseudorhodoferax genus and other Comamonadaceae were detected. Conclusions. The presence of undescribed QepA variants in GenBank is reported and the presence of related sequences among members of Burkholderiales order is described.

Título traducido de la contribuciónIn silico analysis of transferable QepA variants and related chromosomal efflux pumps
Idioma originalEspañol
Páginas (desde-hasta)537-541
Número de páginas5
PublicaciónRevista Espanola de Quimioterapia
Volumen31
N.º6
EstadoPublicada - dic. 2018

Palabras clave

  • Comamonadaceae
  • QepA
  • Transferable mechanisms of quinolone resistance

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