A double mutation in the gyrA gene is necessary to produce high levels of resistance to moxifloxacin in Campylobacter spp. clinical isolates

Joaquim Ruiz, Asunción Moreno, M. Teresa Jimenez De Anta, Jordi Vila

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

18 Citas (Scopus)

Resumen

The aim of this study was to compare different fluoroquinolones against Campylobacter spp., analysing the molecular mechanisms of resistance. Moxifloxacin exhibited the greatest activity of the quinolones tested, being active against isolates carrying a single mutation in the gyrA gene. High resistance levels to moxifloxacin were related to the presence of a double gyrA mutation.

Idioma originalInglés
Páginas (desde-hasta)542-545
Número de páginas4
PublicaciónInternational Journal of Antimicrobial Agents
Volumen25
N.º6
DOI
EstadoPublicada - jun. 2005

Huella

Profundice en los temas de investigación de 'A double mutation in the gyrA gene is necessary to produce high levels of resistance to moxifloxacin in Campylobacter spp. clinical isolates'. En conjunto forman una huella única.

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