TY - JOUR
T1 - Toxoplasmosis congénita
T2 - La importancia de la adherencia a las guías y las implicaciones clínicas en Colombia
AU - Alvarado-Socarras, Jorge L.
AU - Zárate, Andrea
AU - Rodríguez-Morales, Alfonso J.
AU - Guerrero, Carlos F.
AU - Giraldo, John M.
N1 - Publisher Copyright:
© 2020 Hospital Infantil de México Federico Gómez. Publicado por Permanyer.
PY - 2021/7/1
Y1 - 2021/7/1
N2 - Background: Congenital toxoplasmosis continues to be a public health problem. Although clinical guidelines have been divulgated and are well known, they are not implemented in some health institutions, in addition of an inappropriate interpretation of the serological tests in pregnant women. This situation can lead to lack of screening and treatment in pregnant women with primary Toxoplasma gondii infection. Case reports: We report two cases of congenital toxoplasmosis, one with a fatal outcome. In both cases, the clinical guidelines were not initially followed, leading to a delayed diagnosis and, consequently, an inappropriate management in conditions with severe damage. Conclusions: Toxoplasmosis is a congenital infection still prevalent in some countries, with severe sequelae, neurological disability, and even late risk of ocular damage. Additionally, some varieties of the T. gondii strains have a more aggressive pattern in Latin America, worsening the clinical presentation of cases and including a high risk of death.
AB - Background: Congenital toxoplasmosis continues to be a public health problem. Although clinical guidelines have been divulgated and are well known, they are not implemented in some health institutions, in addition of an inappropriate interpretation of the serological tests in pregnant women. This situation can lead to lack of screening and treatment in pregnant women with primary Toxoplasma gondii infection. Case reports: We report two cases of congenital toxoplasmosis, one with a fatal outcome. In both cases, the clinical guidelines were not initially followed, leading to a delayed diagnosis and, consequently, an inappropriate management in conditions with severe damage. Conclusions: Toxoplasmosis is a congenital infection still prevalent in some countries, with severe sequelae, neurological disability, and even late risk of ocular damage. Additionally, some varieties of the T. gondii strains have a more aggressive pattern in Latin America, worsening the clinical presentation of cases and including a high risk of death.
KW - Cerebral toxoplasmosis
KW - Colombia
KW - Congenital toxoplasmosis
KW - Toxoplasmosis
UR - http://www.scopus.com/inward/record.url?scp=85111749613&partnerID=8YFLogxK
U2 - 10.24875/BMHIM.20000238
DO - 10.24875/BMHIM.20000238
M3 - Artículo
C2 - 34351889
AN - SCOPUS:85111749613
SN - 0539-6115
VL - 78
SP - 370
EP - 375
JO - Boletin Medico del Hospital Infantil de Mexico
JF - Boletin Medico del Hospital Infantil de Mexico
IS - 4
ER -