TOXOPLASMOSIS CONGÉNITA CON ENFERMEDAD NEUROLÓGICA SEVERA EN UN HOSPITAL DE REFERENCIA DEL PERÚ

Translated title of the contribution: CONGENITAL TOXOPLASMOSIS WITH SEVERE NEUROLOGICAL DISEASE IN A REFERRAL HOSPITAL IN PERU

Julio Maquera-Afaray, Medalit Luna-Vilchez, Blanca Salazar-Mesones, Christian Chiara-Chilet, Alexander Cordero-Campos, José W. López

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The aim of this study was to describe the epidemiological, clinical, and therapeutic characteristics of patients diagnosed with congenital toxoplasmosis (CT) with severe neurological disease. We reviewed the medical records of patients under 1 year of age with positive IgM test for Toxoplasma gondii and brain, eye, and/or hearing involvement. This study was carried out at the Instituto Nacional de Salud del Niño San Borja (INSNSB), Lima, Peru. Twenty-one patients diagnosed with CT were evaluated; 57.1% were female, and the median age at diagnosis was 3.1 months (IQR: 1.7-7.3). The main central nervous system manifestations were hydrocephalus (76.2%), intracranial calcifications (52.4%), microcephaly (42.9%), and convulsions (25.6%); the most frequent ocular manifestation was chorioretinitis (38.1%). In conclusion, 64% of CT cases had one or more manifestations of severe neurological disease.

Translated title of the contributionCONGENITAL TOXOPLASMOSIS WITH SEVERE NEUROLOGICAL DISEASE IN A REFERRAL HOSPITAL IN PERU
Original languageSpanish
Pages (from-to)208-213
Number of pages6
JournalRevista Peruana de Medicina Experimental y Salud Publica
Volume39
Issue number2
DOIs
StatePublished - 2022

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