Testing Novel Inactivation Methods and Adjuvants for Vaccines Against Streptococcus agalactiae in Nile Tilapia Oreochromis niloticus

Fernando Carlos Ramos-Espinoza, Victor Alexander Cueva-Quiroz, Jefferson Yunis-Aguinaga, Norquis Caled Alvarez-Rubio, Nicoli Paganoti de Mello, Julieta Rodini Engrácia de Moraes

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Inactivation by hydrogen peroxide and pH manipulation are two novel methods used recently in experimental vaccines against Streptococcus agalactiae in Nile tilapia. Here we describe in detail inactivation using novel methods as well as the classical method of inactivation. These vaccines showed similar moderate efficacy when compared to the conventional formaldehyde vaccine. In addition, we describe the inclusion of adjuvants in a hydrogen peroxide vaccine.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages241-249
Number of pages9
DOIs
StatePublished - 2022
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume2411
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Aluminum hydroxide
  • Bacterial inactivation
  • Hydrogen peroxide
  • Streptococcosis
  • Vaccination

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