Testicular cancer mortality in Latin America and the Caribbean: trend analysis from 1997 to 2019

Yuleizy Crispin-Rios, Mariafe Faura-Gonzales, J. Smith Torres-Roman, Carlos Quispe-Vicuña, Uriel S. Franco-Jimenez, Bryan Valcarcel, Andreas Stang, Katherine A. McGlynn

Research output: Contribution to journalArticlepeer-review


Background: In the last decades, an increasing incidence of testicular cancer has been observed in several countries worldwide. Although mortality rates have been variable in many countries, little information is available from Latin America and the Caribbean (LAC). Therefore, we examined mortality trends of testicular cancer in the last two decades. Methods: Age-standardized mortality rates (ASMR) of testicular cancer per 100,000 men-years were estimated using the World Health Organization mortality database from 1997 to 2019. We examined the mortality trends and computed annual percent change (APC) for all ages and the following age groups, 15–29, 30–44, 15–44, and ≥ 45 years. Results: Ten countries had mortality rates greater than 0.43 per 100,000 men, with the highest rates for Chile, Mexico, and Argentina. Significant increases in mortality rates were observed in Argentina, Brazil Colombia, and Mexico in all ages, and < 45 years, while Colombia, Ecuador, Mexico, and Peru reported significant downward trends in males aged ≥ 45 years. Only Chile showed significant decreases for all ages and age groups studied. Conclusion: Mortality by testicular cancer increased among LAC countries in males of all ages and across age groups. A reduction in mortality rates was observed only in Chilean males of all ages and in men ≥ 45 years in several countries. Strengthening of early detection among symptomatic males may decrease the mortality by this neoplasm.

Original languageEnglish
Article number1038
JournalBMC Cancer
Issue number1
StatePublished - Dec 2023


  • Caribbean Region
  • Latin America
  • Mortality
  • Testicular neoplasms


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