Reporte de caso de resistencia al ganciclovir en enfermedad por citomegalovirus postrasplante cardiaco

Translated title of the contribution: Resistance to ganciclovir in cytomegalovirus infection after heart transplant: Case report

Christian Rojas-Contreras, Gabriel De La Cruz-Ku, Stalin Vilcarromero, Ruben Villacaqui Ayllon, Bryan Valcarcel-Valdivia

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Cytomegalovirus infection after a heart transplant is a recurrent medical condition. Its frequency increases when the donors are serum-positive, and the recipients are serum-negative to this virus. In the pediatric population, the infection only develops in a small percentage and the patients rarely present resistance to conventional treatment with ganciclovir and valganciclovir. We presented the first report of a pediatric case of the cytomegalovirus infection resistant to ganciclovir and valganciclovir after a heart transplant in a Peruvian public hospital with an unusual presentation. The resistance to these drugs was evident after 277 days of evolution of the disease considering the non-remission of the symptomatology and the persistence of an elevated viral load. The administration of foscarnet led to a clinical and laboratory improvement until remission of the disease.

Translated title of the contributionResistance to ganciclovir in cytomegalovirus infection after heart transplant: Case report
Original languageSpanish
Pages (from-to)145-149
Number of pages5
JournalRevista Peruana de Medicina Experimental y Salud Publica
Volume35
Issue number1
DOIs
StatePublished - 1 Jan 2018
Externally publishedYes

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