TY - JOUR
T1 - Rendimiento en pruebas cognitivas breves, de adultos mayores con demencia en estadios avanzados, residentes de una comunidad urbana De Lima, Perú
AU - Custodio, Nilton
AU - Alva-Diaz, Carlos
AU - Becerra-Becerra, Yahaira
AU - Montesinos, Rosa
AU - Lira, David
AU - Herrera-Pérez, Eder
AU - Castro-Suárez, Sheila
AU - Cuenca-Alfaro, José
AU - Valeriano-Lorenzo, Elizabeth
N1 - Publisher Copyright:
© 2016, Instituto Nacional de Salud. All rights reserved.
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Objectives. Evaluate the performance of clock drawing test- Manos versión (PDR-M) and Mini Mental State Examination - Peruvian version (MMSE) to detect dementia in a sample based on urban community of Lima, Peru. Materials and methods. This study is a secondary analysis database, observational, analytical and cross-sectional, the gold standard was the clinical and the neuropsychological evaluations together. Performance testing individually and in combination were evaluated.. Data were obtained from prevalence study conducted in 2008 in Cercado de Lima. Results. MMSE performance for evaluation of patients with dementia of any kind showed sensitivity of 64,1%, specificity of 84,1%, PPV of 24.4%, NPV of 96.7%, PLR of 4,03 and NLR of 0,43. PDR-M showed sensitivity of 89,3%, specificity of 98,1%, PPV of 79.3%, NPV of 99.1%, PLR of 47,79 and NLR of 0,11. When both tests were applied, and at least one of them was positive, they showed sensitivity 98.1%, specificity 84.1%, PPV of 33.1%, NPV of 99.8%, PLR of 6,17 and NLR of 0,02. When performing separate analysis of Alzheimer-type dementia and non- Alzheimer dementia, the values of the parameters do not differ substantially from those obtained for dementia of any kind. Conclussions. The combination of MMSE and PDR-M show good discriminative ability to detect moderate and severe dementia in population living in urban community in Lima.
AB - Objectives. Evaluate the performance of clock drawing test- Manos versión (PDR-M) and Mini Mental State Examination - Peruvian version (MMSE) to detect dementia in a sample based on urban community of Lima, Peru. Materials and methods. This study is a secondary analysis database, observational, analytical and cross-sectional, the gold standard was the clinical and the neuropsychological evaluations together. Performance testing individually and in combination were evaluated.. Data were obtained from prevalence study conducted in 2008 in Cercado de Lima. Results. MMSE performance for evaluation of patients with dementia of any kind showed sensitivity of 64,1%, specificity of 84,1%, PPV of 24.4%, NPV of 96.7%, PLR of 4,03 and NLR of 0,43. PDR-M showed sensitivity of 89,3%, specificity of 98,1%, PPV of 79.3%, NPV of 99.1%, PLR of 47,79 and NLR of 0,11. When both tests were applied, and at least one of them was positive, they showed sensitivity 98.1%, specificity 84.1%, PPV of 33.1%, NPV of 99.8%, PLR of 6,17 and NLR of 0,02. When performing separate analysis of Alzheimer-type dementia and non- Alzheimer dementia, the values of the parameters do not differ substantially from those obtained for dementia of any kind. Conclussions. The combination of MMSE and PDR-M show good discriminative ability to detect moderate and severe dementia in population living in urban community in Lima.
KW - Alzheimer’s disease
KW - Dementia
KW - Diagnostic Techniques
KW - Differential diagnosis
KW - Neurological (source: MeSH NLM)
KW - Sensitivity and Specificity
UR - http://www.scopus.com/inward/record.url?scp=85013393330&partnerID=8YFLogxK
U2 - 10.17843/rpmesp.2016.334.2549
DO - 10.17843/rpmesp.2016.334.2549
M3 - Artículo
C2 - 28327834
AN - SCOPUS:85013393330
SN - 1726-4634
VL - 33
SP - 652
EP - 669
JO - Revista Peruana de Medicina Experimental y Salud Publica
JF - Revista Peruana de Medicina Experimental y Salud Publica
IS - 4
ER -