Quinolone resistance in enterotoxigenic Escherichia coli causing diarrhea in travelers to India in comparison with other geographical areas

Jordi Vila, Martha Vargas, Joaquim Ruiz, Manuel Corachan, M. Teresa Jimenez De Anta, Joaquim Gascon

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

Enterotoxigenic Escherichia coli isolates were identified as a cause of traveler's diarrhea in 82 of 520 (16%) patients and tested for resistance to seven antimicrobial agents. Thirty patients (36%) needed antimicrobial therapy: 17 (56%) for persistence of symptoms and 13 (44%) for severity of symptoms. Ampicillin, tetracycline, and trimethoprim-sulfamethoxazole resistance was high. Chloramphenicol showed moderate activity, and amoxicillin plus clavulanic acid, nalidixic acid, and ciprofloxacin showed very good activity. Five nalidixic acid-resistant strains were isolated, four from patients visiting India.

Original languageEnglish
Pages (from-to)1731-1733
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume44
Issue number6
DOIs
StatePublished - 2000

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