TY - JOUR
T1 - Pulmonary alveolar proteinosis
T2 - a case report
AU - Concepción-Urteaga, Luis Alberto
AU - Rodríguez-Hidalgo, Luis Alejandro
AU - Cornejo-Portella, Jorge Luis
AU - Alquizar-Horna, Oscar Neri
AU - Aguilar-Villanueva, Daniel Anderson
AU - Concepción-Zavaleta, Marcio José
AU - Azañero-Luján, Mario Gustavo
PY - 2017/9/14
Y1 - 2017/9/14
N2 - CONCLUSION: Pulmonary alveolar proteinosis is a rare lung disease and important to consider due to the diagnostic and therapeutic challenge it represents.INTRODUCTION: Pulmonary alveolar proteinosis is a rare, diffuse interstitial lung disease, characterized by alveolar obstruction due to the accumulation of pulmonary surfactant.CLINICAL PRESENTATION: A 30-year-old male with progressively worsening dyspnea and non-productive cough for one year. He was a sugar cane plantation worker and had prior recurrent respiratory infections. Physical exam revealed cyanosis, and bilateral coarse and fine rales. Chest computed tomography showed diffuse crazy paving pattern. Bronchoscopy with bronchoalveolar lavage yielded a foamy, thick whitish material. Cytology revealed lymphocytes and acellular proteinaceous eosinophilic material. Transbronchial biopsy confirmed the diagnosis of pulmonary alveolar proteinosis. Patient met criteria for whole lung lavage, responding favorably to this therapy.
AB - CONCLUSION: Pulmonary alveolar proteinosis is a rare lung disease and important to consider due to the diagnostic and therapeutic challenge it represents.INTRODUCTION: Pulmonary alveolar proteinosis is a rare, diffuse interstitial lung disease, characterized by alveolar obstruction due to the accumulation of pulmonary surfactant.CLINICAL PRESENTATION: A 30-year-old male with progressively worsening dyspnea and non-productive cough for one year. He was a sugar cane plantation worker and had prior recurrent respiratory infections. Physical exam revealed cyanosis, and bilateral coarse and fine rales. Chest computed tomography showed diffuse crazy paving pattern. Bronchoscopy with bronchoalveolar lavage yielded a foamy, thick whitish material. Cytology revealed lymphocytes and acellular proteinaceous eosinophilic material. Transbronchial biopsy confirmed the diagnosis of pulmonary alveolar proteinosis. Patient met criteria for whole lung lavage, responding favorably to this therapy.
KW - bronchoalveolar lavage
KW - interstitial lung disease
KW - pulmonary alveolar proteinosis
UR - http://www.scopus.com/inward/record.url?scp=85049205382&partnerID=8YFLogxK
U2 - 10.5867/medwave.2017.08.7040
DO - 10.5867/medwave.2017.08.7040
M3 - Artículo
C2 - 28914826
AN - SCOPUS:85049205382
SN - 0717-6384
VL - 17
SP - e7040
JO - Medwave
JF - Medwave
IS - 8
ER -
