Prevalence of H. pylori Infection in Relatives of Peruvian Patients with Gastric Cancer

Miluska Castillo; Luis A. Bernabe; Carlos A. Castañeda; Nancy Suarez; Fernando Barreda; Daniel Valdivia; Eloy Ruiz; Jais Nieves; Emmanuel Dias-Neto; Maria Landa-Baella; Jennifer Montano-Flores; Iván Chavez

doi:10.31557/apjcc.2021.6.1.53-57

Prevalence of H. pylori Infection in Relatives of Peruvian Patients with Gastric Cancer

Miluska Castillo, Luis A. Bernabe, Carlos A. Castañeda, Nancy Suarez, Fernando Barreda, Daniel Valdivia, Eloy Ruiz, Jais Nieves, Emmanuel Dias-Neto, Maria Landa-Baella, Jennifer Montano-Flores, Iván Chavez

Medicina humana

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Objective: The aim of this study was to determine the relationship between Helicobacter pylori (H. pylori) infection in relatives and patients with gastric cancer (GC). Methods: H. pylori infection was evaluated by the breath urease test in 171 relatives and by qPCR technique in gastric tissue of 61 patients (n=45 for GC and n=16 for non-GC). Results: There were included 137 relatives of GC patients and 34 of non-GC. The median age of the relatives of patients with a gastric tissue sample was 39 years (10-86). Infection was found in 60.2% (n=103) relatives. There were no higher H. pylori infection rates in relatives of patients with gastric cancer (62% vs 62.9%, p=0.33), H. pylori infection (60% vs 60%, p=0.96), or metaplasia (58.8% vs 61.8%, p=0.71). Conclusion: The prevalence of infection in relatives of GC patients is high in our population but not associated with H. pylori presence in the paired case.

Original language	English
Pages (from-to)	53-57
Number of pages	5
Journal	Asian Pacific Journal of Cancer Care
Volume	6
Issue number	1
DOIs	https://doi.org/10.31557/apjcc.2021.6.1.53-57
State	Published - 2021

Keywords

Gastric cancer
Helicobacter pylori
detection
relatives
risk factor

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.31557/apjcc.2021.6.1.53-57

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title = "Prevalence of H. pylori Infection in Relatives of Peruvian Patients with Gastric Cancer",

abstract = "Objective: The aim of this study was to determine the relationship between Helicobacter pylori (H. pylori) infection in relatives and patients with gastric cancer (GC). Methods: H. pylori infection was evaluated by the breath urease test in 171 relatives and by qPCR technique in gastric tissue of 61 patients (n=45 for GC and n=16 for non-GC). Results: There were included 137 relatives of GC patients and 34 of non-GC. The median age of the relatives of patients with a gastric tissue sample was 39 years (10-86). Infection was found in 60.2% (n=103) relatives. There were no higher H. pylori infection rates in relatives of patients with gastric cancer (62% vs 62.9%, p=0.33), H. pylori infection (60% vs 60%, p=0.96), or metaplasia (58.8% vs 61.8%, p=0.71). Conclusion: The prevalence of infection in relatives of GC patients is high in our population but not associated with H. pylori presence in the paired case.",

keywords = "Gastric cancer, Helicobacter pylori, detection, relatives, risk factor",

author = "Miluska Castillo and Bernabe, {Luis A.} and Casta{\~n}eda, {Carlos A.} and Nancy Suarez and Fernando Barreda and Daniel Valdivia and Eloy Ruiz and Jais Nieves and Emmanuel Dias-Neto and Maria Landa-Baella and Jennifer Montano-Flores and Iv{\'a}n Chavez",

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language = "Ingl{\'e}s",

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T1 - Prevalence of H. pylori Infection in Relatives of Peruvian Patients with Gastric Cancer

AU - Castillo, Miluska

AU - Bernabe, Luis A.

AU - Castañeda, Carlos A.

AU - Suarez, Nancy

AU - Barreda, Fernando

AU - Valdivia, Daniel

AU - Ruiz, Eloy

AU - Nieves, Jais

AU - Dias-Neto, Emmanuel

AU - Landa-Baella, Maria

AU - Montano-Flores, Jennifer

AU - Chavez, Iván

PY - 2021

Y1 - 2021

N2 - Objective: The aim of this study was to determine the relationship between Helicobacter pylori (H. pylori) infection in relatives and patients with gastric cancer (GC). Methods: H. pylori infection was evaluated by the breath urease test in 171 relatives and by qPCR technique in gastric tissue of 61 patients (n=45 for GC and n=16 for non-GC). Results: There were included 137 relatives of GC patients and 34 of non-GC. The median age of the relatives of patients with a gastric tissue sample was 39 years (10-86). Infection was found in 60.2% (n=103) relatives. There were no higher H. pylori infection rates in relatives of patients with gastric cancer (62% vs 62.9%, p=0.33), H. pylori infection (60% vs 60%, p=0.96), or metaplasia (58.8% vs 61.8%, p=0.71). Conclusion: The prevalence of infection in relatives of GC patients is high in our population but not associated with H. pylori presence in the paired case.

AB - Objective: The aim of this study was to determine the relationship between Helicobacter pylori (H. pylori) infection in relatives and patients with gastric cancer (GC). Methods: H. pylori infection was evaluated by the breath urease test in 171 relatives and by qPCR technique in gastric tissue of 61 patients (n=45 for GC and n=16 for non-GC). Results: There were included 137 relatives of GC patients and 34 of non-GC. The median age of the relatives of patients with a gastric tissue sample was 39 years (10-86). Infection was found in 60.2% (n=103) relatives. There were no higher H. pylori infection rates in relatives of patients with gastric cancer (62% vs 62.9%, p=0.33), H. pylori infection (60% vs 60%, p=0.96), or metaplasia (58.8% vs 61.8%, p=0.71). Conclusion: The prevalence of infection in relatives of GC patients is high in our population but not associated with H. pylori presence in the paired case.

KW - Gastric cancer

KW - Helicobacter pylori

KW - detection

KW - relatives

KW - risk factor

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M3 - Artículo

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SN - 2588-3682

VL - 6

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JO - Asian Pacific Journal of Cancer Care

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Prevalence of H. pylori Infection in Relatives of Peruvian Patients with Gastric Cancer

Abstract

Keywords

UN SDGs

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