TY - JOUR
T1 - Multiple endocrine neoplasia type 1 with brown tumors as first manifestation in a patient with pituitary adenoma
T2 - A case report
AU - Manrique-Franco, Katty
AU - Ibarcena-Llerena, Claudia Vanessa
AU - Gutierrez, Geraldine Espinoza
AU - Chambergo-Michilot, Diego
N1 - Publisher Copyright:
© 2022 by Author/s and Licensed by Modestum.
PY - 2022/8
Y1 - 2022/8
N2 - Introduction: Multiple endocrine neoplasia type 1 (MEN 1) is an infrequent autosomal dominant hereditary syndrome. Common manifestations are related to hypercalcemia, which is caused by primary hyperparathyroidism (PHPT). Brown tumors are infrequent as initial presentation of PHPT associated with MEN 1. It occurs in less than 2% of MEN 1 population. Results: A 36-year-old woman started the disease 25 years ago in an insidious and progressive manner. She presented a soft tumor in the left malar region that progressively increased in volume. We treated recurrent multiple brown tumors in a patient with PHPT and pituitary adenoma. Conclusion: The follow-up was demanding and multidisciplinary. The long-term prognosis is uncertain; therefore, close monitoring of the patient should be carried out through clinical, laboratory and imaging evaluation.
AB - Introduction: Multiple endocrine neoplasia type 1 (MEN 1) is an infrequent autosomal dominant hereditary syndrome. Common manifestations are related to hypercalcemia, which is caused by primary hyperparathyroidism (PHPT). Brown tumors are infrequent as initial presentation of PHPT associated with MEN 1. It occurs in less than 2% of MEN 1 population. Results: A 36-year-old woman started the disease 25 years ago in an insidious and progressive manner. She presented a soft tumor in the left malar region that progressively increased in volume. We treated recurrent multiple brown tumors in a patient with PHPT and pituitary adenoma. Conclusion: The follow-up was demanding and multidisciplinary. The long-term prognosis is uncertain; therefore, close monitoring of the patient should be carried out through clinical, laboratory and imaging evaluation.
KW - case reports
KW - multiple endocrine neoplasia type 1
KW - osteitis fibrosa cystica
KW - pituitary neoplasms
KW - recklinghausen’s disease of bone
UR - http://www.scopus.com/inward/record.url?scp=85133389588&partnerID=8YFLogxK
U2 - 10.29333/ejgm/12077
DO - 10.29333/ejgm/12077
M3 - Artículo
AN - SCOPUS:85133389588
SN - 2516-3507
VL - 19
JO - Electronic Journal of General Medicine
JF - Electronic Journal of General Medicine
IS - 4
M1 - em384
ER -