Molecular characterization of the integrons in Shigella strains isolated from patients with traveler's diarrhea

M. M. Navia, J. Ruiz, J. Vila

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19 Scopus citations

Abstract

The prevalence and characterization of Class 1 integrons has been performed in eighty three strains of Shigella spp., isolated between 1995 and 2000 from patients with traveler's diarrhea. A low prevalence (13.25%) was recorded. Nine different integrons were found among 11 multiresistant strains, with a total of 10 different gene cassettes encoding for resistance to trimethoprim (dfrA1, dfrA5, dfrA7, dfrA12, and dfrA15), aminoglycosides (aadA1a and aadA2), β-lactam antibiotics (oxa2) or ORF with unknown function (orfD and orfF). A high prevalence of dfr and aad gene cassettes was observed. The low incidence of Class 1 integrons observed in this study is in contrast with the known facility that the Shigella genus has to gain and transfer plasmids.

Original languageEnglish
Pages (from-to)175-179
Number of pages5
JournalDiagnostic Microbiology and Infectious Disease
Volume48
Issue number3
DOIs
StatePublished - Mar 2004

Keywords

  • Antibiotic resistance
  • Gene cassettes
  • Genetic elements

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