TY - JOUR
T1 - Methodological appraisal of the evidence about efficacy of metabolic surgery in adults with non-morbid obesity and hypertension
T2 - An overview of systematic reviews
AU - Cáceres-Távara, María E.
AU - Espinoza-Solano, Carmen G.
AU - Nieto-Gutierrez, Wendy
AU - Delgado-Delgado, Ronald
N1 - Funding Information:
Partial financial support was received from Universidad Cientifica del Sur. This support was acquired through a competition among the students of that university and their graduate theses. The university was not involved in the study design, data collection, analysis or interpretation; nor was it involved in the writing of the report or in the decision to submit the article for publication.
Publisher Copyright:
© 2022
PY - 2022/8
Y1 - 2022/8
N2 - Background: Nowadays, the high morbimortality of obesity is mainly related to diabetes, cancer, and hypertension. It is reported that obesity in patients with hypertension can lead to resistance to pressure reduction through pharmacological therapy and lifestyle changes, so bariatric surgery emerges as a proposed treatment for obesity. Methods: We performed an umbrella review that included systematic reviews of clinical trials that evaluated patients with hypertension and non-morbid obesity. The quality and certainty of the evidence was evaluated with the AMSTAR-II and GRADE tools. Results: 677 systematic reviews were identified, of which only three were included for analysis. We considered the outcomes addressed by the reviews on hypertension, identifying that 5 RCTs evaluated pressure reduction at 1 year of follow-up and 5 RCTs at more than 1 year, 5 RCTs evaluated hypertension rate, 6 RCTs analyzed changes in systolic pressure and 5 RCTs changes in diastolic pressure. Likewise, when assessing the methodological quality, it was concluded that the three reviews have critically low quality. Conclusions: We found only three systematic reviews that evaluated the topic with critically low methodological quality. They reported results in favor of metabolic surgery, but with very low certainty of evidence.
AB - Background: Nowadays, the high morbimortality of obesity is mainly related to diabetes, cancer, and hypertension. It is reported that obesity in patients with hypertension can lead to resistance to pressure reduction through pharmacological therapy and lifestyle changes, so bariatric surgery emerges as a proposed treatment for obesity. Methods: We performed an umbrella review that included systematic reviews of clinical trials that evaluated patients with hypertension and non-morbid obesity. The quality and certainty of the evidence was evaluated with the AMSTAR-II and GRADE tools. Results: 677 systematic reviews were identified, of which only three were included for analysis. We considered the outcomes addressed by the reviews on hypertension, identifying that 5 RCTs evaluated pressure reduction at 1 year of follow-up and 5 RCTs at more than 1 year, 5 RCTs evaluated hypertension rate, 6 RCTs analyzed changes in systolic pressure and 5 RCTs changes in diastolic pressure. Likewise, when assessing the methodological quality, it was concluded that the three reviews have critically low quality. Conclusions: We found only three systematic reviews that evaluated the topic with critically low methodological quality. They reported results in favor of metabolic surgery, but with very low certainty of evidence.
KW - Bariatric surgery
KW - Hypertension
KW - Metabolic surgery. (source: MeSH)
KW - Obesity
UR - http://www.scopus.com/inward/record.url?scp=85132529960&partnerID=8YFLogxK
U2 - 10.1016/j.ijsu.2022.106716
DO - 10.1016/j.ijsu.2022.106716
M3 - Artículo de revisión
C2 - 35732261
AN - SCOPUS:85132529960
SN - 1743-9191
VL - 104
JO - International Journal of Surgery
JF - International Journal of Surgery
M1 - 106716
ER -
