Malignant syphilis as the presenting complaint of advanced HIV

Juan José Montenegro-Idrogo, Ricardo Muñante, Manuel López-Fuentes, María Sanz-Castro, Alex Ventura-León, Gonzalo Chávez-Esparza, Yuri García-Cortez

Research output: Contribution to journalArticlepeer-review


Malignant syphilis is an infrequent secondary manifestation in patients with human immunodeficiency virus (HIV), with polymorphous and disseminated skin lesions being related to severe immunosuppression. Lesions have intense inflammatory circinate, ulcer-crusted and nodular skin lesions of diffuse distribution throughout the body, that can be confused with vasculitis or cutaneous lymphomas. We report a patient recently diagnosed with HIV infection in the acquired immunodeficiency syndrome stage with malignant syphilis as the debut of HIV.

Original languageEnglish
Pages (from-to)494-497
Number of pages4
JournalInternational Journal of STD and AIDS
Issue number7
StatePublished - Jun 2023


  • AIDS < viral disease
  • HIV (human immunodeficiency virus) < viral disease
  • Syphilis (treponema pallidum) < bacterial disease


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