Lipschütz acute vulvar ulcer related to COVID-19 vaccination: First case report in South America

Lucero Sangster-Carrasco; Romario Paz-Temoche; Julia Coronado-Arroyo; Marcio Concepción-Zavaleta; Pela Roseboom; Luis Concepción-Urteaga; Francisca Zavaleta-Gutiérrez

doi:10.5867/medwave.2023.02.2674

Lipschütz acute vulvar ulcer related to COVID-19 vaccination: First case report in South America

Lucero Sangster-Carrasco, Romario Paz-Temoche, Julia Coronado-Arroyo, Marcio Concepción-Zavaleta, Pela Roseboom, Luis Concepción-Urteaga, Francisca Zavaleta-Gutiérrez

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Lipschütz ulcer is a non-sexually transmitted genital lesion of unknown etiology, which pres-ents as a painful vulvar ulcer. Lipschütz ulcers have been described in most continents. This is the first case reported in Peru and South America. We present the case of a 33-year-old female patient with a Lipschütz ulcer after being vaccinated with the second dose of the AstraZeneca COVID-19 vaccine. She reported having had only one sexual partner in her lifetime. Laboratory results were negative for herpes simplex 2, Cytomegalovirus, Toxoplasma gondii, Epstein-Barr virus, and syphilis. The patient received symptomatic treatment. Ten days after the onset, the patient was significantly better during follow-up. This case report displays a potential adverse effect of the AstraZeneca COVID-19 vaccine as a Lipschütz ulcer triggered by the host humoral immune response. However, further research is needed to establish the causal relationship between these two.

Translated title of the contribution	Úlcera vulvar aguda de Lipschütz relacionada con la vacunación por COVID-19: primer caso notificado en Sudamérica
Original language	English
Article number	e2674
Journal	Medwave
Volume	23
Issue number	2
DOIs	https://doi.org/10.5867/medwave.2023.02.2674
State	Published - Mar 2023
Externally published	Yes

Keywords

COVID-19
COVID-19 Vaccine
ChAdOx1 nCoV-19
Coronavirus Disease 2019
Vulvar ulcer

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.5867/medwave.2023.02.2674

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title = "Lipsch{\"u}tz acute vulvar ulcer related to COVID-19 vaccination: First case report in South America",

abstract = "Lipsch{\"u}tz ulcer is a non-sexually transmitted genital lesion of unknown etiology, which pres-ents as a painful vulvar ulcer. Lipsch{\"u}tz ulcers have been described in most continents. This is the first case reported in Peru and South America. We present the case of a 33-year-old female patient with a Lipsch{\"u}tz ulcer after being vaccinated with the second dose of the AstraZeneca COVID-19 vaccine. She reported having had only one sexual partner in her lifetime. Laboratory results were negative for herpes simplex 2, Cytomegalovirus, Toxoplasma gondii, Epstein-Barr virus, and syphilis. The patient received symptomatic treatment. Ten days after the onset, the patient was significantly better during follow-up. This case report displays a potential adverse effect of the AstraZeneca COVID-19 vaccine as a Lipsch{\"u}tz ulcer triggered by the host humoral immune response. However, further research is needed to establish the causal relationship between these two.",

keywords = "COVID-19, COVID-19 Vaccine, ChAdOx1 nCoV-19, Coronavirus Disease 2019, Vulvar ulcer",

author = "Lucero Sangster-Carrasco and Romario Paz-Temoche and Julia Coronado-Arroyo and Marcio Concepci{\'o}n-Zavaleta and Pela Roseboom and Luis Concepci{\'o}n-Urteaga and Francisca Zavaleta-Guti{\'e}rrez",

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doi = "10.5867/medwave.2023.02.2674",

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T1 - Lipschütz acute vulvar ulcer related to COVID-19 vaccination

T2 - First case report in South America

AU - Sangster-Carrasco, Lucero

AU - Paz-Temoche, Romario

AU - Coronado-Arroyo, Julia

AU - Concepción-Zavaleta, Marcio

AU - Roseboom, Pela

AU - Concepción-Urteaga, Luis

AU - Zavaleta-Gutiérrez, Francisca

PY - 2023/3

Y1 - 2023/3

N2 - Lipschütz ulcer is a non-sexually transmitted genital lesion of unknown etiology, which pres-ents as a painful vulvar ulcer. Lipschütz ulcers have been described in most continents. This is the first case reported in Peru and South America. We present the case of a 33-year-old female patient with a Lipschütz ulcer after being vaccinated with the second dose of the AstraZeneca COVID-19 vaccine. She reported having had only one sexual partner in her lifetime. Laboratory results were negative for herpes simplex 2, Cytomegalovirus, Toxoplasma gondii, Epstein-Barr virus, and syphilis. The patient received symptomatic treatment. Ten days after the onset, the patient was significantly better during follow-up. This case report displays a potential adverse effect of the AstraZeneca COVID-19 vaccine as a Lipschütz ulcer triggered by the host humoral immune response. However, further research is needed to establish the causal relationship between these two.

AB - Lipschütz ulcer is a non-sexually transmitted genital lesion of unknown etiology, which pres-ents as a painful vulvar ulcer. Lipschütz ulcers have been described in most continents. This is the first case reported in Peru and South America. We present the case of a 33-year-old female patient with a Lipschütz ulcer after being vaccinated with the second dose of the AstraZeneca COVID-19 vaccine. She reported having had only one sexual partner in her lifetime. Laboratory results were negative for herpes simplex 2, Cytomegalovirus, Toxoplasma gondii, Epstein-Barr virus, and syphilis. The patient received symptomatic treatment. Ten days after the onset, the patient was significantly better during follow-up. This case report displays a potential adverse effect of the AstraZeneca COVID-19 vaccine as a Lipschütz ulcer triggered by the host humoral immune response. However, further research is needed to establish the causal relationship between these two.

KW - COVID-19

KW - COVID-19 Vaccine

KW - ChAdOx1 nCoV-19

KW - Coronavirus Disease 2019

KW - Vulvar ulcer

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DO - 10.5867/medwave.2023.02.2674

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AN - SCOPUS:85150834934

SN - 0717-6384

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JO - Medwave

JF - Medwave

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ER -

Lipschütz acute vulvar ulcer related to COVID-19 vaccination: First case report in South America

Abstract

Keywords

UN SDGs

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