Level of knowledge about metalloproteinases in dental students close to graduate from three universities in Peruvian capital city

César F. Cayo-Rojas, Lilliam Soto-Castro, Manuel Castro-Mena, Sara Medrano-Colmenares, Carlos López-Gurreonero, Nancy Córdova-Limaylla, Gissela Briceño-Vergel, Marysela Ladera-Castañeda, Luis Cervantes-Ganoza

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Background: Metalloproteinases are proteolytic enzymes that degrade dentin and periodontal collagen; therefore, it is of special interest that dental students know its mechanism of action and how its effects can be inhibited. Therefore, the aim of this research was to evaluate the level of knowledge about metalloproteinases in dental students close to graduate from three universities in Peruvian capital city. Materials and methods: In this analytical, observational, cross-sectional and prospective study, 223 dental students close to graduate in three Peruvian universities were evaluated from September to November 2020. A questionnaire of 20 closed questions with three answers was validated and used to measure the level of general and dental knowledge about metalloproteinases. A logit model was used to evaluate the influence of the following variables: “gender” (X1), “type of university” (X2), “marital status” (X3) and “age group” (X4), in the knowledge levels of the students, considering a p-value <.05. Results: Of the 223 dentistry students, it was obtained that the level of knowledge about metalloproteinases was predominantly low with 82.1%, (95% confidence interval (CI): 77.1%–87.1%) of the total. According to multivariate logistic regression analysis, "type of university" was the only variable that proved to have a significant influence (p =.022) on the level of knowledge about metalloproteinases with an odds ratio of (OR = 0.44; CI: 0.21–0.89), whilst the other variables "age group" (p >.05), "gender" (p =.058) and "marital status" (p =.114) were not considered influential factors. Conclusion: The majority of final year dental students in three Peruvian universities presented a low level of overall knowledge about metalloproteinases. In addition, private university students were 56% less likely to pass the subject knowledge test. On contrary, gender, age group and marital status did not significantly influence the level of knowledge of the students.

Original languageEnglish
Pages (from-to)692-699
Number of pages8
JournalEuropean Journal of Dental Education
Volume26
Issue number4
DOIs
StatePublished - Nov 2022
Externally publishedYes

Keywords

  • dental students
  • dentistry
  • knowledge
  • metalloproteinase inhibitors
  • metalloproteinases
  • Peru

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