TY - JOUR
T1 - Lepra
T2 - Sospecha diagnóstica en área no endémica. Serie de casos y revisión de la literatura
AU - Mendez-Guerra, Carolina
AU - Montenegro-Idrogo, Juan José
AU - Resurrección-Delgado, Cristhian
AU - Quevedo-Ramírez, Andrés
AU - Cornejo-Venegas, Gonzalo
AU - Berrio-Martínez, Sabja
AU - Arévalo-Abanto, Jorge
AU - Chiappe-Gonzalez, Alfredo
N1 - Publisher Copyright:
© 2020 Colegio Medico del Peru. All rights reserved.
PY - 2020/8/18
Y1 - 2020/8/18
N2 - Leprosy (Hansen’s disease) is a chronic granulomatous condition caused by Mycobacteriumleprae, a microorganism that affects the skin and Schwann’s cells. Making a diagnosis of this condition is difficult in non-endemic areas because of low clinical suspicion. During the 2012-2019 time period, three cases of Hansen’s disease were diagnosed and treated in the ID service of Dos de Mayo Hospital. The average time history of the disease was 4 years. Patients started their condition with the appearance of pruriginous papular lesions affecting specific body regions, progressing to generalized nodular lesions. Paresthesia and tactile, thermal, pain, and vibratory hypoesthesia were found. These manifestations later progressed to anesthesia. Diagnosis was made through bacilloscopy in lymphatic fluid and skin node biopsy. Clinical features for each patient are also described. We emphasize the importance of clinical suspicion for diagnosing this unattended disease in non-endemic areas.
AB - Leprosy (Hansen’s disease) is a chronic granulomatous condition caused by Mycobacteriumleprae, a microorganism that affects the skin and Schwann’s cells. Making a diagnosis of this condition is difficult in non-endemic areas because of low clinical suspicion. During the 2012-2019 time period, three cases of Hansen’s disease were diagnosed and treated in the ID service of Dos de Mayo Hospital. The average time history of the disease was 4 years. Patients started their condition with the appearance of pruriginous papular lesions affecting specific body regions, progressing to generalized nodular lesions. Paresthesia and tactile, thermal, pain, and vibratory hypoesthesia were found. These manifestations later progressed to anesthesia. Diagnosis was made through bacilloscopy in lymphatic fluid and skin node biopsy. Clinical features for each patient are also described. We emphasize the importance of clinical suspicion for diagnosing this unattended disease in non-endemic areas.
KW - Clinical diagnosis
KW - Leprosy
KW - Leprosy, borderline
KW - Mycobacterium leprae
UR - http://www.scopus.com/inward/record.url?scp=85167993608&partnerID=8YFLogxK
U2 - 10.35663/amp.2020.373.910
DO - 10.35663/amp.2020.373.910
M3 - Artículo
AN - SCOPUS:85167993608
SN - 1018-8800
VL - 37
SP - 346
EP - 351
JO - Acta Medica Peruana
JF - Acta Medica Peruana
IS - 3
ER -