TY - JOUR
T1 - Infección por el complejo Mycobacterium avium-intracellulare en pacientes con VIH/SIDA en un hospital Peruano
T2 - Una serie de casos
AU - Ticona-Huaroto, César
AU - Astocondor-Salazar, Lilian
AU - Montenegro-Idrogo, Juan
AU - Valencia-Mesias, Gustavo
AU - Soria, Jaime
N1 - Publisher Copyright:
© 2017, Instituto Nacional de Salud. All rights reserved.
PY - 2017/4/1
Y1 - 2017/4/1
N2 - There is little information on the presence of the Mycobacterium avium-Intracellulare (MAC) complex in Peru. Five cases of MAC infection are described in patients with HIV/AIDS at the National Hospital Dos de Mayo, Lima – Peru. The patients presented, mainly, persistent fever, chronic diarrhea, consumptive syndrome, pancytopenia and citofagocitosis. In all of them, resistant acid-alcohol bacilli were identified in feces, so they received antituberculous treatment. The culture of feces was negative for Mycobacterium tuberculosis and, later, in all cases MAC was identified using a molecular test (genotype) in the culture of feces. Three patients received treatment for MAC right after identification; however, they all died. Before presentations similar to the reported, we suggest the use of higher performance methods (blood culture, myeloculture, molecular tests), as well as early associating drugs with activity for MAC to antitubercular scheme with the intention of improving the prognosis of this group of patients.
AB - There is little information on the presence of the Mycobacterium avium-Intracellulare (MAC) complex in Peru. Five cases of MAC infection are described in patients with HIV/AIDS at the National Hospital Dos de Mayo, Lima – Peru. The patients presented, mainly, persistent fever, chronic diarrhea, consumptive syndrome, pancytopenia and citofagocitosis. In all of them, resistant acid-alcohol bacilli were identified in feces, so they received antituberculous treatment. The culture of feces was negative for Mycobacterium tuberculosis and, later, in all cases MAC was identified using a molecular test (genotype) in the culture of feces. Three patients received treatment for MAC right after identification; however, they all died. Before presentations similar to the reported, we suggest the use of higher performance methods (blood culture, myeloculture, molecular tests), as well as early associating drugs with activity for MAC to antitubercular scheme with the intention of improving the prognosis of this group of patients.
KW - Acquired immunodeficiency syndrome (source: MeSH NLM)
KW - HIV-1
KW - Mycobacterium avium complex
UR - http://www.scopus.com/inward/record.url?scp=85028973060&partnerID=8YFLogxK
U2 - 10.17843/rpmesp.2017.342.2476
DO - 10.17843/rpmesp.2017.342.2476
M3 - Artículo
C2 - 29177395
AN - SCOPUS:85028973060
SN - 1726-4634
VL - 34
SP - 323
EP - 327
JO - Revista Peruana de Medicina Experimental y Salud Publica
JF - Revista Peruana de Medicina Experimental y Salud Publica
IS - 2
ER -