Guía de Práctica Clínica para el manejo de pacientes con Leucemia Linfoblástica Aguda en el Seguro Social del Perú (EsSalud)

Translated title of the contribution: Clinical practice guideline for the management of patients with acute lymphoblastic leukemia in Peruvian Social Security (EsSalud)

Ninoska Rojas Soto, Mariela Moreno Larrea, Marlies Pizarro Perea, Lourdes Aranda Gomero, Cecilia Arteta Altamirano, Renee Eyzaguirre Zapata, Sergio Goicochea-Lugo, Wendy Nieto- Gutierrez, Franko O. Garcia-Solorzano, Alvaro Taype-Rondan, Raúl Timaná Ruiz

Research output: Contribution to journalArticlepeer-review

Abstract

This paper summarizes the evidence-based clinical recommendations for the assessment and management of patients with acute lymphoblastic leukemia (ALL) in Peruvian Social Security (EsSalud). A guide writing team (GWT) was convened, which included specialized physicians and methodologists. The GWT asked 8 clinical questions to be responded by the Clinical Practice Guidelines (CPG). Detailed searches of systematic reviews and – when it was considered as pertinent – primary studied featured in PubMed and CENTRAL during 2019 were performed. Evidence for responding each of the proposed clinical questions was selected. Certainty of the evidence was determined using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. In scheduled workshops, the GWT used the GRADE methodology for reviewing the evidence and propose recommendations, the points for good clinical practice, and the assessment and management flowcharts. This CPG worked on 8 clinical questions, which were divided in 4 topics: diagnosis, general measures, chemotherapy management for ALL, and transplantation. On the basis of these questions, 5 recommendations were formulated (3 strong recommendations and 2 conditional recommendations), 20 points for good clinical practice, and 3 flow charts.

Translated title of the contributionClinical practice guideline for the management of patients with acute lymphoblastic leukemia in Peruvian Social Security (EsSalud)
Original languageSpanish
Pages (from-to)64-78
Number of pages15
JournalActa Medica Peruana
Volume38
Issue number1
DOIs
StatePublished - Apr 2021
Externally publishedYes

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