TY - JOUR
T1 - Evolución y manejo del síndrome inflamatorio multisistémico pediátrico asociado a infecciónporSARSCoV-2enunaUCIpediátricadeLima,Perú
AU - Cieza-Yamunaqué, Liliana
AU - Rodriguez-Portilla, Ricardo
AU - Baique-Sanchez, Michael
AU - Coila-Paricahua, Edgar
AU - Guerra-Ríos, Claudia
AU - Llaque-Quiroz, Patricia
AU - Pinedo-Torres, Isabel Angélica
N1 - Publisher Copyright:
© 2021 Medical Body of the Almanzor Aguinaga Asenjo National Hospital. All rights reserved.
PY - 2021/11
Y1 - 2021/11
N2 - Background: Pediatric Multisystemic Inflammatory Syndrome (SIMP) associated with SARS CoV2 seriously affects children. Objective: To describe the symptoms, treatment and evolution of SIMP in patients of a reference Pediatric Intensive Care Unit (PICU). Findings: 18 children were identified with a mean age of 8.76 years, 50% male, all with a positive serological test. The most frequent manifestations were: fever (100%), respiratory distress (94%), abdominal pain (89%), elevated C-reactive protein (average 21.8), thrombocytopenia (50%), pathological chest X-ray (89%) and depressed myocardial contractility (61%). 72% required invasive mechanical ventilation (average 3 days) and catecholamines; 89% used corticosteroids plus immunoglobulins. The average stay in the PICU was 5.5 days. One patient died of intracerebral hemorrhage. Conclusions: SIMP in PICU is characterized by fever, respiratory distress, abdominal pain, elevated inflammatory markers, and myocardial depression. Requiring corticosteroids, immunoglobulin and ventilatory support; presenting intermediate stay and low mortality.
AB - Background: Pediatric Multisystemic Inflammatory Syndrome (SIMP) associated with SARS CoV2 seriously affects children. Objective: To describe the symptoms, treatment and evolution of SIMP in patients of a reference Pediatric Intensive Care Unit (PICU). Findings: 18 children were identified with a mean age of 8.76 years, 50% male, all with a positive serological test. The most frequent manifestations were: fever (100%), respiratory distress (94%), abdominal pain (89%), elevated C-reactive protein (average 21.8), thrombocytopenia (50%), pathological chest X-ray (89%) and depressed myocardial contractility (61%). 72% required invasive mechanical ventilation (average 3 days) and catecholamines; 89% used corticosteroids plus immunoglobulins. The average stay in the PICU was 5.5 days. One patient died of intracerebral hemorrhage. Conclusions: SIMP in PICU is characterized by fever, respiratory distress, abdominal pain, elevated inflammatory markers, and myocardial depression. Requiring corticosteroids, immunoglobulin and ventilatory support; presenting intermediate stay and low mortality.
KW - Child
KW - Covid-19
KW - Critical care
KW - Lymphonodular mucocutaneous syndrome
KW - Peru
KW - Therapeutics
UR - http://www.scopus.com/inward/record.url?scp=85122975055&partnerID=8YFLogxK
U2 - 10.35434/rcmhnaaa.2021.143.1216
DO - 10.35434/rcmhnaaa.2021.143.1216
M3 - Artículo
AN - SCOPUS:85122975055
SN - 2225-5109
VL - 14
SP - 262
EP - 266
JO - Revista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo
JF - Revista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo
IS - 3
ER -