Epidemiology and clinical presentation of shigellosis in children less than five years of age in rural Mozambique

Inácio Mandomando, Betuel Sigaúque, Xavier Vallès, Mateu Espasa, Sergi Sanz, Jahit Sacarlal, Eusébio Macete, Fátima Abacassamo, Joaquim Ruiz, Joaquim Gascon, Karen L. Kotloff, Myron M. Levine, Pedro L. Alonso

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Rectal swabs were collected from 1354 children <5 years of age with diarrhea attending Manhiça District Hospital and from 227 healthy community controls. Shigellosis incidence was high among children aged 12-47 months (488.4/10 child-years at risk). Fever and dysentery were prominent clinical findings. Shigella was more frequently isolated from cases than controls (6.7% versus 0.4%, P = 0.004), and from dysentery than nondysenteric diarrhea (24.1% versus 3.5%, P < 0.001). Shigella flexneri 2a, S. sonnei, and S. flexneri 6, were the most prevalent serotypes.

Original languageEnglish
Pages (from-to)1059-1061
Number of pages3
JournalPediatric Infectious Disease Journal
Volume26
Issue number11
DOIs
StatePublished - Nov 2007

Keywords

  • Antimicrobial resistance
  • Bacillary dysentery
  • Serotypes
  • Shigella

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