TY - JOUR
T1 - Efecto analgésico de la asociación de diclofenaco y vitaminas B1, B6 y B12 en cirugía de tercer molar
AU - Chumpitaz-Cerrate, Victor
AU - Sánchez-Huamaní, Juan
AU - Chávez-Rimache, Lesly
AU - Castro-Rodríguez, Yuri
AU - Rodríguez-Flores, Arturo
AU - Franco-Quino, César
N1 - Publisher Copyright:
© 2019 SECOM.
PY - 2019
Y1 - 2019
N2 - Objective: To evaluate the analgesic effect of the administration of the association of diclofenac with B vitamins in patients undergoing elective mandibular third molar surgery. Material and method: Randomized controlled double blind clinical trial that included 70 patients divided into 2 groups, one group received diclofenac plus B vitamins (experimental) and the other only diclofenac (control). The main variable was pain intensity according to visual analog scale (VAS) after 1, 3, 6, 9, 12 and 24 hours after the surgery was completed; the secondary variables were the time for rescue analgesia and the total consumption of analgesics in the postoperative period. Results: The pain intensity was increased in both groups until 6 hours (p > 0.05). At 24 hours, the highest pain intensity was perceived in both study groups, being significantly lower in the experimental group (3.21 ± 1.31) compared to the control group (4.89 ± 1.42); p = 0.035. The time for rescue analgesia was significantly higher in the experimental group (11.32 ± 2.31 hours) compared to the control group (8.93 ± 1.91 hours); p = 0.001. The total analgesic consumption was lower in the experimental group (6.17 ± 1.42 tablets) compared to the control group (6.49 ± 0.97 tablets); p = 0.10. Conclusion: The administration of the association of diclofenac with vitamins B showed a greater analgesic effect compared to only diclofenac in patients undergoing elective mandibular third molar surgery.
AB - Objective: To evaluate the analgesic effect of the administration of the association of diclofenac with B vitamins in patients undergoing elective mandibular third molar surgery. Material and method: Randomized controlled double blind clinical trial that included 70 patients divided into 2 groups, one group received diclofenac plus B vitamins (experimental) and the other only diclofenac (control). The main variable was pain intensity according to visual analog scale (VAS) after 1, 3, 6, 9, 12 and 24 hours after the surgery was completed; the secondary variables were the time for rescue analgesia and the total consumption of analgesics in the postoperative period. Results: The pain intensity was increased in both groups until 6 hours (p > 0.05). At 24 hours, the highest pain intensity was perceived in both study groups, being significantly lower in the experimental group (3.21 ± 1.31) compared to the control group (4.89 ± 1.42); p = 0.035. The time for rescue analgesia was significantly higher in the experimental group (11.32 ± 2.31 hours) compared to the control group (8.93 ± 1.91 hours); p = 0.001. The total analgesic consumption was lower in the experimental group (6.17 ± 1.42 tablets) compared to the control group (6.49 ± 0.97 tablets); p = 0.10. Conclusion: The administration of the association of diclofenac with vitamins B showed a greater analgesic effect compared to only diclofenac in patients undergoing elective mandibular third molar surgery.
KW - Analgesia
KW - Diclofenac
KW - Third molar surgery
KW - Vitamin B complex
UR - http://www.scopus.com/inward/record.url?scp=85091821816&partnerID=8YFLogxK
U2 - 10.20986/recom.2019.1010/2018
DO - 10.20986/recom.2019.1010/2018
M3 - Artículo
AN - SCOPUS:85091821816
SN - 1130-0558
VL - 41
SP - 68
EP - 74
JO - Revista Espanola de Cirugia Oral y Maxilofacial
JF - Revista Espanola de Cirugia Oral y Maxilofacial
IS - 2
ER -