Diagnóstico del Síndrome de Guillain-Barré y uso de los criterios de Brighton en hospitales Peruanos

Translated title of the contribution: Diagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals

Marco Malaga, Aaron Rodriguez-Calienes, Victor Velasquez-Rimachi, Carlos Alva-Diaz

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Guillain-Barré syndrome (GBS) is an autoimmune disease of the peripheral nervous system that caused multiple epidemiological outbreaks in Peru during 2018 and 2019. It is usually diagnosed using the Brighton criteria (BC). Objective: We aimed to determine the performance of Peruvian neurologists in diagnosing GBS based on the BC, along with its associated factors. Methods: This was a retrospective multicenter cohort study. We included patients diagnosed with GBS between 2007 and 2018 in three public hospitals in Lima, Peru. We collected data regarding demographic, clinical and management characteristics. We evaluated the use of the BC for confirmatory diagnosis of GBS and developed a logistic regression model to identify factors associated with its use. Results: Out of 328 cases, we reviewed 201 available charts. The median age was 48 years, with male predominance. Over half of the patients presented an inadequate motor examination according to their Medical Research Council (MRC) score. Additional testing included lumbar puncture and electrophysiological testing, in over 70% of the cases. The BC showed certainty level 1 in 13.4% and levels 2 and 3 in 18.3%. Neither the quality of the motor examination nor the type of institution showed any association with the BC. Conclusions: Level 1 diagnostic certainty of the BC was met in less than one quarter of the cases with a GBS diagnosis in three centers in Lima, Peru, between 2007 and 2018. This level was not significantly associated with being treated in a specialized institute, rather than in a general hospital.

Translated title of the contributionDiagnosis of Guillain-Barré syndrome and use of Brighton criteria in Peruvian hospitals
Original languageSpanish
Pages (from-to)601-606
Number of pages6
JournalArquivos de Neuro-Psiquiatria
Volume80
Issue number6
DOIs
StatePublished - Jun 2022

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